In vitro synergistic/antagonistic antibacterial and anti-inflammatory effect of various extracts/essential oil from cones of Tetraclinis articulata (Vahl) Masters with antibiotic and anti-inflammatory agents

Djouahri, Abderrahmane; Saka, Boualem; Boudarene, Lynda; Benseradj, Fadhéla; Aberrane, Sihem; Aitmoussa, Samira; Chelghoum, C.; Lamari, Lynda; Sabaou, Nasserdine; Baâliouamer, Aoumeur

doi:10.1016/j.indcrop.2014.02.035

Cited by 49 publications

(36 citation statements)

References 20 publications

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“…Apart from proven antioxidant properties, many monoterpenes were shown to be characterized by one or more of the following activities: anticancer, antimicrobial or inhibitory, towards selected enzymes . Synergistic interactions have been proven for some isoprene derivatives for the inhibitory effect towards acetylcholinesterase, nematicidal and antimicrobial activity . Ahmad et al .…”

Section: Introductionmentioning

confidence: 99%

Antioxidant synergism and antagonism between selected monoterpenes using the 2,2‐diphenyl‐1‐picrylhydrazyl method

Cieśla

Wojtunik-Kulesza

Oniszczuk

et al. 2016

Flavour & Fragrance J

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This research aims to investigate synergistic and antagonistic antioxidant interactions for binary mixtures of common monoterpenes. The activity was determined spectrophotometrically with the use of the DPPH• assay. Significant antioxidant synergism, between two different monoterpenes, was observed for a mixture of inactive p‐cymene and one of the compounds, characterized by moderate antioxidant activity, e.g. (±)‐citronellal, α‐phellandrene or α‐terpinene. It has been proven that the activity of (±)‐citronellal is increased in the presence of hydrocarbons possessing the aromatic nucleophilic ring, which may react with electrophiles. A possible reaction mechanism was proposed for the synergistic antioxidant effect of p‐cymene and (±)‐citronellal. This research opens new perspectives for studying interactions between isoprene derivatives, found in essential oils. Copyright © 2016 John Wiley & Sons, Ltd.

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Section: Introductionmentioning

confidence: 99%

Antioxidant synergism and antagonism between selected monoterpenes using the 2,2‐diphenyl‐1‐picrylhydrazyl method

Cieśla

Wojtunik-Kulesza

Oniszczuk

et al. 2016

Flavour & Fragrance J

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“…(2014) 10 and Djouahri et al. (2013) 17 , which revealed that Algerian T. articulata essential oil had an excellent inflammatory activity using the Lipoxygenase inhibition and Xanthine oxidase inhibition assays.…”

Section: Resultsmentioning

confidence: 97%

“…Among several T. articulata extracts that may be useful as bioactive natural plant products, essential oil was reported to possess potent antibacterial,10, 11, 12, 13 antifungal14, 15 and antioxidant activities,16, 17 mediated by the major monoterpene component α-pinene, limonene, camphor, borneol and bornyl acetate 18, 19, 20, 21. The high monoterpenes content was also described as being responsible for antitumor activity of T. articulata essential oil 22, 23.…”

Section: Introductionmentioning

confidence: 99%

Chemical composition, acute toxicity, antioxidant and anti-inflammatory activities of Moroccan Tetraclinis articulata L.

Jemli¹,

Kamal²,

Marmouzi³

et al. 2017

Journal of Traditional and Complementary Medicine

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Hydro-distilled essential oil (EO) from the leaves of the western Mediterranean and Moroccan endemic plant Tetraclinis articulata was analyzed by GC/MS and examined for its acute toxicity on mice, in order to establish the safe doses. Furthermore, the anti-Inflammatory activity was evaluated based on carrageenan and trauma induced rats paw edema and the antioxidant potential has been investigated using different methods including DPPH radical-scavenging assay, Trolox equivalent antioxidant capacity (TEAC) and Ferric-reducing antioxidant power assay (FRAP). The major identified compounds in GC/MS analysis were bornyl acetate (26.81%), camphor (22.40%) and α-pinene (7.16%), with 25 other minor constituents. No mortalities in acute toxicity were observed, indicating that the LD50 of T. articulata essential oil is highest than 5 g/kg. In the anti-inflammatory test based on chemical and mechanical induced trauma, the EO demonstrated an effective reduce swelling by 64.71 ± 9.38% and 69.09 ± 6.02% respectively obtained 6 h after administration at the dose of 200 mg/kg when compared to the control groups. Moreover in the antioxidant testing battery, T. articulata essential oil showed a promising scavenging effect measured by DPPH, TEAC and ferric-reducing power assays with IC50 values of 12.05 ± 0.24 mg/mL, 8.90 ± 0.17 mg/mL and 0.15 ± 0.01 mg/mL respectively. These results suggest that, the EO from the leaves of T. articulata constitutes a valuable source of anti-inflammatory and antioxidant metabolites. These findings argue for the possible integration of this oil in pharmaceutical, cosmetic and food industries.

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“…This tree is used in traditional and popular medicine to cure numerous infections both in childhood and adulthood: respiratory and intestinal infections, gastric pains, diabetes, hypertension and rheumatism (Bourkhiss et al, 2007;Bourkhiss et al, 2010). It was observed that this plant not only has antibacterial and antifungal effects (Bourkhiss et al, 2007;Bourkhiss et al, 2010;Djouahri et al, 2014), but it also possesses cytotoxic, antioxidative, and anti-inflammatory characteristics (Djouahri and Boudarene, 2012). Having in mind a broad spectrum of treated illnesses, the chemical composition of Thuja articulata (Vahl) has been successfully evaluated (Djouahri et al, 2013).…”

Section: Cytotoxicitymentioning

confidence: 99%

Inhibitory effects of medical plants on the Candida albicans and bacterial growth in the oral cavity

Tambur

Cenic-Milosevic²,

Miljkovic-Selimovic

et al. 2017

Zb Mat srp prir nauk

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In this mini-review, the authors discuss the effects of ethanol extracts, essential oils and cytotoxicity of some medicinal plants and their compounds used in ethnomedicine in different geographic regions worldwide, including Serbia, on the growth, multiplication and pathogenicity of Candida albicans and bacteria that play the main role in the balance of the oral ecosystem. Various medicinal plants, such as Rosmarinus officinalis (Fam. Lamiaceae), Artemisia dracunculus, Artemisia absinthium (Fam. Asteraceae), exist in different geographic regions and continents, as well as in the Balkan region, and among them there are some indigenous species like Hypericum perforatum L. (Fam. Hypericaceae), Urtica dioica L. (U. dioica) (Fam. Urticaceae), Achillea millefolium L. (Fam. Asteraceae), Matricaria chamomilla L. (Fam. Asteraceae), Sambucus nigra L. (Fam. Caprifoliaceae), and Thymus serpyllum L. (Fam. Lamiaceae) with impressive antimicrobial activity against microorganisms originating from the oral cavity.

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In vitro synergistic/antagonistic antibacterial and anti-inflammatory effect of various extracts/essential oil from cones of Tetraclinis articulata (Vahl) Masters with antibiotic and anti-inflammatory agents

Cited by 49 publications

References 20 publications

Antioxidant synergism and antagonism between selected monoterpenes using the 2,2‐diphenyl‐1‐picrylhydrazyl method

Antioxidant synergism and antagonism between selected monoterpenes using the 2,2‐diphenyl‐1‐picrylhydrazyl method

Chemical composition, acute toxicity, antioxidant and anti-inflammatory activities of Moroccan Tetraclinis articulata L.

Inhibitory effects of medical plants on the Candida albicans and bacterial growth in the oral cavity

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