2020
DOI: 10.1016/j.jgar.2020.04.005
|View full text |Cite
|
Sign up to set email alerts
|

In vitro tripanocidal effect of 1,8-dioxooctahydroxanthenes (xanthenodiones) and tetraketones and improvement of cardiac parameters in vivo

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
4
1

Citation Types

0
8
0

Year Published

2021
2021
2024
2024

Publication Types

Select...
8

Relationship

2
6

Authors

Journals

citations
Cited by 10 publications
(8 citation statements)
references
References 58 publications
0
8
0
Order By: Relevance
“…1,8-Dioxa-octahydroanthracene compounds have extremely high pharmacological activity and use value in the fields of dyes and photosensitive materials and are antibacterial and anti-inflammatory, so they are considered to be the most practical type of heterocyclic compounds . In recent years, many catalysts utilized to catalyze the formation of heteroanthracene molecules have been widely reported. However, need toxic solvents, metal loss pollutes water, harsh reaction conditions, the amount of catalyst used is enormous and cannot be recovered, and the low product yield persists. In this work, affordable and industrially manufactured poly­(aluminum chloride) and silica gel were utilized as catalysts, and heteroanthracene compounds were prepared using a one-pot process under mechanical grinding.…”
Section: Resultsmentioning
confidence: 99%
“…1,8-Dioxa-octahydroanthracene compounds have extremely high pharmacological activity and use value in the fields of dyes and photosensitive materials and are antibacterial and anti-inflammatory, so they are considered to be the most practical type of heterocyclic compounds . In recent years, many catalysts utilized to catalyze the formation of heteroanthracene molecules have been widely reported. However, need toxic solvents, metal loss pollutes water, harsh reaction conditions, the amount of catalyst used is enormous and cannot be recovered, and the low product yield persists. In this work, affordable and industrially manufactured poly­(aluminum chloride) and silica gel were utilized as catalysts, and heteroanthracene compounds were prepared using a one-pot process under mechanical grinding.…”
Section: Resultsmentioning
confidence: 99%
“…Tetraketones are an important class of bioactive compounds that have been used as a tyrosinase inhibitor, 13 laser dye, 14 and mainly as a lipoxygenase inhibitor and antioxidant agent, 15 as well as amastigote growth inhibitior 16 (Fig. 1).…”
Section: Introductionmentioning
confidence: 99%
“…Since most of the cases are diagnosticated during the chronic phase and, at this time, the trypanocidal effectiveness of benznidazole is partial without reduction of cardiac clinical disturbances (Morillo et al, 2015), studies with new potential drugs or compounds are desirable to the development of a preventive and/or curative treatment. Potential natural/chemical compounds have been investigated to control parasite and the immune response in different infected tissues (De Paula Costa et al, 2016;Menezes et al, 2020).…”
Section: Introductionmentioning
confidence: 99%