In vivo alanine/EPR dosimetry in daily clinical practice: a feasibility study

Ciesielski, B.; Schultka, K.; Kobierska, A; Nowak, Renata; Peimel-Stuglik, Zofia

doi:10.1016/s0360-3016(03)00196-2

Cited by 44 publications

(29 citation statements)

References 32 publications

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“…Factor (1) refers to the spectrometer sensitivity, storage and measurements conditions of DLalanine dosimeters. According to previous reports (Dolo and Feaugas, 2005;Ciesielski et al, 2003;Nagy, 2000;Alexandre et al, 1992), the procedure used in storage and the dosimeter reading error adds uncertainties less than 3%, as shown in Table 1. Therefore, larger differences between planned and measured doses cannot be attributed to ESR measurements.…”

Section: In Vivo Assessmentmentioning

confidence: 94%

“…They can be used also to evaluate dose to the rectum during gynecological treatments (Sha et al, 2011;Wang et al, 2010;Lambert et al, 2007;Waldh€ ausl et al, 2005;Sakata et al, 2002;Deshpande et al, 1997). An in vivo dosimetric method of interest is alanine/Electron Spin Resonance (ESR) dosimetry (De Angelis et al, 1999;Kuntz et al, 1996;Schaeken and Scalliet, 1996), that has been used in different clinical practices (Baffa and Kinoshita, 2014;Wagner et al, 2008;Schultka et al, 2006;Ciesielski et al, 2003).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Measurement of rectum dose by in vivo alanine/ESR dosimetry in gynecological 192Ir HDR brachytherapy

Bravo-Miranda

Rech

Oliveira

et al. 2015

Radiation Measurements

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Section: In Vivo Assessmentmentioning

confidence: 94%

Section: Introductionmentioning

confidence: 99%

Measurement of rectum dose by in vivo alanine/ESR dosimetry in gynecological 192Ir HDR brachytherapy

Bravo-Miranda

Rech

Oliveira

et al. 2015

Radiation Measurements

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“…Numerous works have tackled this issue using different detectors as underlined in a recent Vision 20/20 manuscript by Tanderup et al . Two major problems with those detectors are related to the use of non‐water equivalent material and the incapacity of making real‐time measurement . The former concern is usually responsible for detector energy dependance and the latter points out the fact that some treatment errors can be invisible to integral dose measurements .…”

Section: Introductionmentioning

confidence: 99%

Technical Note: Identification of an optimal electromagnetic sensor for in vivo electromagnetic‐tracked scintillation dosimeter for HDR brachytherapy

Tho

Beaulieu

2019

Medical Physics

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Purpose Brachytherapy is a treatment modality which delivers large doses of radiation in a reduced number of visits. Since a small number of large dose‐per‐fraction is administered in high dose rate brachytherapy, ensuring the right dose is delivered is highly critical. In this work, a scintillation detector is coupled to an electromagnetic (EM) sensor (NDI, Waterloo, ON, Canada) having submillimeter positional accuracy for real‐time tracking of the dosimeter position. However, adding an EM sensor adds materials in the path to the scintillator and thus could potentially perturb the dose measurements. This study assesses four different sensors for a plastic scintillation detector–EM sensor coupled dosimeter. Methods To confirm the perturbation presence, different sensors were placed in front of the scintillator so the radiation does not arrive to it directly. Variation of the distance between the sensor and the scintillator was used to quantify the effect on the signal at 0∘ and 90∘. To test the signal's angular dependence for each sensor, the signal measurement was taken from 0∘ to 90∘ with 10∘ increment. Results The Aurora 5DOF‐610090 sensor showed an increased signal of almost 20% with increasing beam angle. Sensors Aurora 5DOF‐610099, Aurora 5DOF‐610157, and Aurora Micro 6DOF‐610059 showed no significant angle dependance. The Aurora Micro 6DOF‐610059 and Aurora 5DOF‐610157 sensors' cable signal revealed no extra signal attenuation. The latter gives a smaller overall attenuation. Therefore, the Aurora 5DOF‐610157 sensor is chosen to be part of the novel dosimeter construction. It has a jitter error (average standard deviation of each individual measurement) of ±0.06 mm and a reproducibility of ±0.008 mm. In the optimal operating range, the average positional uncertainty is less than 0.2 mm. Average angle errors are not higher than 1.1∘. Conclusion It is feasible to integrate an EM tracking sensor to a plastic scintillation dosimeter with minimal impact to the collected signal as well as sufficient positional accuracy to keep dose uncertainty below 5%.

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“…Up to now, most studies were focused on L À a-alanine [30][31][32][33][34][35][36][37][38][39]. At the International Atomic Energy Agency (IAEA), the ESR/alanine dosimetry has become a standard technique to measure high radiation doses (0.1-100 kGy) and is routinely used for transfer dosimetry [40].…”

Section: Introductionmentioning

confidence: 99%

ESR dosimeter material properties of phenols compound exposed to radiotherapeutic electron beams

Gallo

Iacoviello²,

Bartolotta

et al. 2017

Nuclear Instruments and Methods in Physics Research Section B:

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In vivo alanine/EPR dosimetry in daily clinical practice: a feasibility study

Cited by 44 publications

References 32 publications

Measurement of rectum dose by in vivo alanine/ESR dosimetry in gynecological 192Ir HDR brachytherapy

Measurement of rectum dose by in vivo alanine/ESR dosimetry in gynecological 192Ir HDR brachytherapy

Technical Note: Identification of an optimal electromagnetic sensor for in vivo electromagnetic‐tracked scintillation dosimeter for HDR brachytherapy

ESR dosimeter material properties of phenols compound exposed to radiotherapeutic electron beams

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