In Vivo Analgesic Activity of Aqueous Extract from Leaves of Limoniastrum feei

Abstract

Aim of the study: To evaluate analgesic effect of Limoniastrum feei, a medicinal plant from the southeast of Algeria. Two doses (25mg/kg and 30mg/kg) of the crude aqueous extract of leaves from Limoniastrum feei were evaluated for analgesic activity using acetic acid induced writhing in mice. The two doses (25,30mg/kg) of the extract tested were effective. The extract at the tested doses produced a percentage inhibition of the acetic acid induced abdominal constriction of (33.39 and 35.38%), respectively. The crude extract produced a statistically significant analgesic activity comparable to the effect of standard drug (50mg/kg Diclofenac). This study demonstrated the potential analgesic properties of crude aqueous extract of leaves from Limoniastrum feei.