In vivo and in vitro evolution of the effects of cypermethrin on turbot (Scophthalmus maximus, Linnaeus, 1758) spermatozoa

The adverse effects of tetramethrin residues, a synthetic pyrethroid used in many insecticide formulations, on environmental health and living organisms are a matter of concern. The aim of this study was to evaluate the genotoxic and developmental effects of tetramethrin in a non-target organism, Drosophila melanogaster. Thus, its effect on DNA damage was evaluated using the comet assay in hemocytes, and its mutagenic and recombinogenic effects were evaluated using Drosophila wing SMART. Also, the effects of tetramethrin on Drosophila development were evaluated by measuring larval weight, larval length, and fertility. Results showed that tetramethrin induced a decrease in the larval weight and length only at a high concentration. Moreover, a decrease in fertility in a dose-dependent manner was observed. According to the comet results, DNA damage was not induced because there was no significant increase in %DNA. However, tetramethrin caused genotoxicity by inducing mitotic recombination in the SMART assay.

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In vivo and in vitro evolution of the effects of cypermethrin on turbot (Scophthalmus maximus, Linnaeus, 1758) spermatozoa

Cited by 4 publications

References 72 publications

Chronic cypermethrin induced toxicity and molecular fate assessment within common carp (Cyprinus carpio) using multiple biomarkers approach and its novel therapeutic detoxification

Chronic cypermethrin induced toxicity and molecular fate assessment within common carp (Cyprinus carpio) using multiple biomarkers approach and its novel therapeutic detoxification

Effects of 2,4-dichlorophenol on non–specific immunity, histopathological lesions, and redox balance in African Catfish, clarias gariepinus (Burchell, 1822)

Investigation of Genotoxic and Development Effects of Tetramethrin on Drosophila melanogaster

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