In vivo Antibacterial and Wound Healing Activities of Roman Chamomile (Chamaemelum nobile)

Abstract

Our study indicated that antibacterial and wound healing activities of C. nobile ointment were notable. C. nobile therapy in combination with antibiotics can also be useful because medicinal plants contents operate in synergy with antibiotics. These results revealed the value of plant extracts to control antibiotic resistant bacteria in wound infections.

Green and Chemical Silver Nanoparticles and Pomegranate Formulations to Heal Infected Wounds in Diabetic Rats

“…During this process, re-epithelialization, fibroplasia, angiogenesis, and extracellular matrix production are important steps that are generally dependent on the immunological condition of the host [ 23 , 46 , 47 , 48 ]. The use of natural compounds represents an alternative to chemical compounds used to induce healing, and it showed satisfactory results [ 23 , 24 , 26 , 49 ]; the use of pomegranate extracts to accelerate the healing process was described [ 1 , 22 , 25 , 50 ]. Additionally, silver nanoparticles (AgNPs) have drawn attention due their versatile functions such as antimicrobial, anti-inflammatory, and antiangiogenetic properties, and wound healing promotion, and they are used as interesting tools to overcome emerging medical challenges [ 51 ].…”

“…The use of natural extracts applied as antimicrobial drugs is a growing field in science that has demonstrated interesting and promising results [ 22 , 23 ]. Following this scenario, several plant extracts were studied for the treatment of wound healing, such as extracts from Chrozophora tinctoria , Hibiscus rosa-sinensis L., Pongamia pinnata , Persea americana , Chamaemelum nobile L., and Punica granatum [ 24 , 25 , 26 , 27 , 28 , 29 , 30 ].…”

A Comprehensive Study of Therapeutic Applications of Chamomile

“…It has shown activity against both Gram-positive and Gram-negative bacteria. The antibacterial potential was studied by Kazemian et al [ 36 ]. Wounds were created by incision using a blade and subsequently infected with Pseudomonas aeruginosa strains.…”

Traditional plants from Asteraceae family as potential candidates for functional food industry

“…The results showed that the C. nobile ointment significantly inhibited P. aeruginosa and also stimulated wound healing compared with the control. 115 2.6. E. cannabinum E. cannabinum, commonly known as hemp-agrimony, is a herbaceous plant common in Europe, North America, Central Asia, and Northern Africa.…”