In vivo assessment of antifertility potential of Pteridophytic plants: Actiniopteris radiata (SW.) L. and Selaginella bryopteris (L.) Baker in swiss albino mice

Abstract

Objective: Population explosion is a foremost problem and its control in colonized countries may have an effect on the economic growth, in this regard family planning has been promoted through several methods of contraception, however current methods of contraception result in undesirable side effect. Thus there is a need to replace these agents with potent drugs with least or zero side effects. Hence, the present study was undertaken to evaluate the antifertility properties of and on female albino mice. Actiniopteris radiata Selaginella bryopteris Material and methods: Experimental mice were orally administered with methanol extract of (175 and 300 mg/kg body Actiniopteris radiata weight) and (250 and 500 mg/kg body weight) for 30 days. Effect of the treatment on female Selaginella bryopteris reproductive organ was investigated and level of oestrogen was determined by ECLIA oestrogen standard kit. Quantitative estimations of protein, cholesterol and alkaline phosphatase of blood serum were carried out using Biosystems Diagnostics standard kit. : The treatment showed decrease in weight of the ovary Results and conclusion and decrease in oestrogen level and on the other hand histological changes were also observed. The overall results of the present study revealed that the low dose of (175 mg/kg body weight) methanolic extract of induced infertility A. radiata whereas in high dose (300 mg/kg body weight) it is not observed. While had notshown much significant S. bryopteris variation in female albino mice when compared to control.

The Potential of Jatropha variegata Fruits as a Natural Contraceptive: Antifertility Activity and Phytochemical Analysis

“…e histological findings of this study suggest a hypothalamic-pituitary-gonadal axis dysfunction after treatment with the plant extract through a negative feedback mechanism of the gonadotropins FSH and LH as previously explained [43]. In accordance, several plants have been shown to act in a similar fashion [43,[46][47][48][49][50][51][52].…”

Deleterious effect of short-term gavage of an ethanol extract of cogon grass (Imperata cylindrica L.) roots on testis and epididymal sperm quality

“…Herbs and medicinal plants have the potential to be used as antifertility agents. Many investigations have been carried out to validate the antifertility properties of plants, such as Bacolepis nervosa [ 4 ], Barleria prionitis [ 5 ], Actiniopteris radiata (SW.) L., and Selaginella bryopteris (L.) [ 6 ]. Moreover, one study reported on 48 plants that have antifertility potential [ 7 ], but many plants have not been investigated yet.…”