In vivo assessment of dichlorvos induced histological and biochemical impairments coupled with expression of p53 responsive apoptotic genes in the liver and kidney of fish, Channa punctatus (Bloch, 1793)

Assessment of the Exposure of Two Pesticides on Common Carp (Cyprinus Carpio Linnaeus, 1758): Are the Prolonged Biomarker Responses Adaptive or Destructive?

“…We agree with Trivedi et al (2021) that water pollution may cause oxidative stress-associated molecular damage, which in turn reflects in the impairment of tissue and organ architecture. The histological analysis revealed different affection degrees in each target organ (liver > gills) of common carp exposed to CYP and CPF, which was probably due to the specific function and sensitivity of each organ as noted by Costa et al (2013) and Cuevas et al (2016).…”

Ethanolic root extract of Rauwolfia serpentina alleviates copper induced genotoxicity and hepatic impairments in spotted snakehead fish, Channa punctatus (Bloch, 1793)

“…This culminates into cytogenetic instability including DNA damage. DNA strand breaks are mainly responsible for the formation of MN (Trivedi et al, 2021). The frequency of MN induction was significantly (p < 0.05) increased in Group-III with an increasing fold-change of 3.25 < 3.40 < 4.30 < 7.38 after 24, 48, 72 and 96 hr exposure periods, respectively, as compared to control (Fig.…”

Effects of polystyrene nanoplastics on apoptosis, digestive enzymes, and intestinal histological structure and flora of swamp eel (Monopterus albus)

“…When cells are stimulated by apoptotic signals, an increase in p53 activity leads to upregulation of the expression of Bax, which alters the permeability of the mitochondrial membrane. 83,84 This results in leakage of the mitochondrial membrane, releasing cytochrome C and other apoptosis-promoting proteins from the mitochondrial interior. 85,86 The release of cytochrome C activates cysteoaspartase family proteins to form a promoter body complex.…”