In vivo cartilage contact deformation in the healthy human tibiofemoral joint

Bingham, Jeffrey T.; Papannagari, Ramprasad; Velde, Samuel K. Van de; Gross, Christopher; Gill, Thomas J.; Felson, David T.; Rubash, Harry E.; Li, G.

doi:10.1093/rheumatology/ken345

Cited by 126 publications

(142 citation statements)

References 53 publications

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“…They reported that healthy subjects have a medial to lateral tibiofemoral contact area ratio of %1.55 between 0 and 15 of knee flexion. In vivo tibiofemoral cartilage contact deformation was also greater in the medial compartment than the lateral compartment during a single-leg lunge activity (28). The larger contact area in the medial compartment appears to be associated with the geometry of the tibiofemoral articular cartilage, with the medial compartment having a larger contact congruity due to the concave medial tibial plateau compared to the convex lateral tibial plateau (29).…”

Section: Discussionmentioning

confidence: 99%

In vivo tibiofemoral cartilage‐to‐cartilage contact area of females with medial osteoarthritis under acute loading using MRI

Shin

Souza

Kumar

et al. 2011

Magnetic Resonance Imaging

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Purpose: To investigate the effect of acute loading on in vivo tibiofemoral contact area changes in both compartments, and to determine whether in vivo tibiofemoral contact area differs between subjects with medial knee osteoarthritis (OA) and healthy controls. Materials and Methods:Ten subjects with medial knee OA (KL3) and 11 control subjects (KL0) were tested. Coronal three-dimensional spoiled gradient-recalled (3D-SPGR) and T 2 -weighted fast spin-echo FSE magnetic resonance imaging (MRI) of the knee were acquired under both unloaded and loaded conditions. Tibiofemoral cartilage contact areas were measured using image-based 3D models.Results: Tibiofemoral contact areas in both compartments significantly increased under loading (P < 0.001) and the increased contact area in the medial compartment was significantly larger than in the lateral compartment (P < 0.05). Medial compartment contact area was significantly larger in KL3 subjects than KL0 subjects, both at unloaded and loaded conditions (P < 0.05). Contact areas measured from 3D-SPGR and T 2 -weighted FSE images were strongly correlated (r ¼ 0.904). Conclusion:Females with medial OA increased tibiofemoral contact area in the medial compartment compared to healthy subjects under both unloaded and loaded conditions. The contact area data presented in this study may provide a quantitative reference for further cartilage contact biomechanics such as contact stress analysis and cartilage biomechanical function difference between osteoarthritic and healthy knees.

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Section: Discussionmentioning

confidence: 99%

In vivo tibiofemoral cartilage‐to‐cartilage contact area of females with medial osteoarthritis under acute loading using MRI

Shin

Souza

Kumar

et al. 2011

Magnetic Resonance Imaging

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“…[8][9][10][11][12][13][14][15] Combination of MR imaging and double fluoroscopy on knees during motion and various flexion angles show similar results (in healthy subject [16][17][18][19] and in subjects with torn cruciate ligaments [19][20][21] ). On the contrary, gaps among the joint surfaces are a common observation in knee arthroscopic operations.…”

Section: -3mentioning

confidence: 69%

The Tibiofemoral Joint Gaps - An Arthroscopic Study

2017

SDRP-JBE

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Abstract:The articular surfaces of the tibiofemoral jointcommonly appear to have gaps in between during Arthroscopy operations. However, the same joint surfaces appear to be in contact inMR images. This discrepancy may be attributed to the pressure of the saline injected into the joint duringarthroscopy operations, insertion of cannulas, or anesthesia and the resulting absence of compressive force on the joint. This study examines the effect of these factors. Seven candidates of knee arthroscopysurgery participated in the study. The tibiofemoral joint space was observed with the arthroscope in different knee and hip flexion angles, with and without saline pressure, and with and without external compressive load. In the totally extended knee position, the joint was closed on both the lateral and medial sides. In the flexed knee positions, some of the joints showed a gap in either medial or lateral sides or both. Removing saline pressure and applying external compressive force on the knees did not affect the gaps. As this phenomenon cannot be explained with the conventional joint biomechanics, there is a need to revise the biomechanics of the knee joint, probably with the aid of the concepts laid in the theory of biotensegrity.

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“…It should be mentioned that, the patient should be asked to avoid any strenuous activity such as running, lifting and stairclimbing at least 4 hrs prior to the examination. In addition, the patient should be asked to refrain from weight bearing for 1 hr prior the imaging to ensure the knees cartilages are totally recovered from any residual deformation (Bingham et al, 2008).…”

Section: Discussionmentioning

confidence: 99%

The spatio-temporal mechanical environment of healthy and injured human cartilage during sustained activity and its role in cartilage damage

Miramini

Smith

Zhang

et al. 2017

Journal of the Mechanical Behavior of Biomedical Materials

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This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting galley proof before it is published in its final citable form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. AbstractRecently we presented a computational model of articular cartilage calibrated for normal human tissue explants. This model was able to capture the transient deformation of cartilage experiencing a cyclic load. The model takes into account the tension-compression nonlinearity of the cartilage and incorporates the dependency of the compressive stiffness and fluid permeability of cartilage on the deformation-dependent aggrecan concentration in cartilage tissue. As such it represents a leading constitutive model of articular cartilage.Here we build on the previous study to develop an experimentally validated computational

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In vivo cartilage contact deformation in the healthy human tibiofemoral joint

Abstract: These data may provide base-line knowledge for investigating the effects of various knee injuries on joint contact biomechanics and the aetiology of cartilage degeneration.

Cited by 126 publications

References 53 publications

In vivo tibiofemoral cartilage‐to‐cartilage contact area of females with medial osteoarthritis under acute loading using MRI

In vivo tibiofemoral cartilage‐to‐cartilage contact area of females with medial osteoarthritis under acute loading using MRI

The Tibiofemoral Joint Gaps - An Arthroscopic Study

The spatio-temporal mechanical environment of healthy and injured human cartilage during sustained activity and its role in cartilage damage

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