In vivo characterisation of superficial colorectal neoplastic lesions with high-resolution probe-based confocal laser endomicroscopy in combination with video-mosaicing: A feasibility study to enhance routine endoscopy

Palma, Giovanni Domenico De; Staibano, Stefania; Siciliano, S; Persico, Marcello; Masone, Stefania; Maione, Francesco; Siano, Maria; Mascolo, Massimo; Esposito, Dario; Salvatori, Francesca; Persico, Giovanni

doi:10.1016/j.dld.2010.03.009

Cited by 58 publications

(47 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…These features are clearly different from the features of non-neoplastic lesions, such as normal mucosa, hyperplastic or serrated polyps. De Palma et al 27 assessed the accuracy and inter-observer agreement (IOA) of pCLE in colorectal polyps using the Miami Classification, in a study involving 32 small polyps ranging from 1 mm to 9 mm, in 20 patients. Lesions were identified using WLE and then pCLE.…”

Section: Statement Rejectedmentioning

confidence: 99%

Use of probe‐based confocal laser endomicroscopy (pCLE) in gastrointestinal applications. A consensus report based on clinical evidence

et al. 2015

View full text Add to dashboard Cite

Background: Probe-based confocal laser endomicroscopy (pCLE) provides microscopic imaging during an endoscopic procedure. Its introduction as a standard modality in gastroenterology has brought significant progress in management strategies, affecting many aspects of clinical care and requiring standardisation of practice and training. Objective: This study aimed to provide guidance on the standardisation of its practice and training in Barrett's oesophagus, biliary strictures, colorectal lesions and inflammatory bowel diseases. Methods: Initial statements were developed by five group leaders, based on the available clinical evidence. These statements were then voted and edited by the 26 participants, using a modified Delphi approach. After two rounds of votes, statements were validated if the threshold of agreement was higher than 75%. Results: Twenty-six experts participated and, among a total of 77 statements, 61 were adopted (79%) and 16 were rejected (21%). The adoption of each statement was justified by the grade of evidence. Conclusion: pCLE should be used to enhance the diagnostic arsenal in the evaluation of these indications, by providing microscopic information which improves the diagnostic performance of the physician. In order actually to implement this technology in the clinical routine, and to ensure good practice, standardised initial and continuing institutional training programmes should be established.

show abstract

Section: Statement Rejectedmentioning

confidence: 99%

Use of probe‐based confocal laser endomicroscopy (pCLE) in gastrointestinal applications. A consensus report based on clinical evidence

et al. 2015

View full text Add to dashboard Cite

show abstract

“…Microscopic endoscopy technology was originally developed to acquire real-time histologic images at the cellular or subcellular level of superficial mucosal structures. [21][22][23][24] Our results demonstrate that this technology can be expanded for evaluation of the outmost muscularis. Etiologic analyses by using opportunistically obtained surgical specimens have established that dysmotility accompanies abnormalities in the intramural ganglia and the systematic function of the submucosal and/or myenteric plexus.…”

Section: Discussionmentioning

confidence: 87%

In vivo histologic imaging of the muscularis propria and myenteric neurons with probe-based confocal laser endomicroscopy in porcine models (with videos)

Ohya

Sumiyama

Takahashi‐Fujigasaki

et al. 2012

Gastrointestinal Endoscopy

View full text Add to dashboard Cite

“…Its strength lies in confirming dysplasia in identified lesions, with probe based CLE having a 91% accuracy in diagnosing neoplastic polyps and a five time greater dysplasia detection rate in inflammatory bowel disease compared to WLE [43][44][45][46].…”

Section: Clinical Applicabilitymentioning

confidence: 98%

Image-enhanced endoscopy technology in the gastrointestinal tract: What is available?

Beg

Ragunath

2015

Best Practice & Research Clinical Gastroenterology

View full text Add to dashboard Cite

In vivo characterisation of superficial colorectal neoplastic lesions with high-resolution probe-based confocal laser endomicroscopy in combination with video-mosaicing: A feasibility study to enhance routine endoscopy

Cited by 58 publications

References 22 publications

Use of probe‐based confocal laser endomicroscopy (pCLE) in gastrointestinal applications. A consensus report based on clinical evidence

Use of probe‐based confocal laser endomicroscopy (pCLE) in gastrointestinal applications. A consensus report based on clinical evidence

In vivo histologic imaging of the muscularis propria and myenteric neurons with probe-based confocal laser endomicroscopy in porcine models (with videos)

Image-enhanced endoscopy technology in the gastrointestinal tract: What is available?

Contact Info

Product

Resources

About