In Vivo Evaluation of The Novel Nanocomposite Porous 3D Scaffold in a Rabbit Model

Mahmood, Saffanah Khuder; Razak, Intan Shameha Binti Abdul; Ibrahim, S. M.; Yusof, Loqman Mohamad; Abubakar, Adamu Abdul; Mahmood, Zaid Khudhur; Zakaria, Zuki Abu Bakar

doi:10.17485/ijst/2018/v11i19/122540

Indian Journal of Science and Technology

2018

DOI: 10.17485/ijst/2018/v11i19/122540

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In Vivo Evaluation of The Novel Nanocomposite Porous 3D Scaffold in a Rabbit Model

Saffanah Khuder Mahmood¹,

Intan Shameha Binti Abdul Razak²,

S. M. Ibrahim³

et al.

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2023

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Radiographic Evaluation of Bone Healing Following Oral Administration of Bone Broth and Quail Eggs on Experimentally Drilled Femoral Bone Defect in Rabbits

Oviawe,

Fadasan,

Lawal

et al. 2023

Farm Anim. Health Nutr.

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Introduction: Radiography can monitor bone healing to detect delayed healing, non-union, and mal-union early. This study aimed to monitor bone healing, following oral administration of quail eggs and bone broth (BB) on a bone defect in the rabbit model. Materials and methods: A total of 24 adult white New Zealand rabbits were used in the study. They were divided into four six groups before creating a 3.5 mm bone defect. The first group received a daily oral dose of BB, the second group a daily oral dose of quail egg (QE), and the third group received a daily oral dose combination of BB and quail eggs (BQE). At the same time, the fourth group was given an oral daily dose of distilled water (CN) for 12 weeks. Radiographs were taken at 2, 4, 6, 8, 10, and 12 weeks postoperative. An experienced radiologist blinded to the groupings scored the radiographs on a scale of 0-4 based on mineral opacity. Results: At week 6, the BB and BQE groups differed significantly from the QE and CN groups. There was a significant difference between the treatments and the control group at weeks 8 and 10. The complete healing of BB and BQE groups occurred before week 10. The healing of two rabbits in the QE group was done before week 10 although the others completed healing before week 12. The CN group did not heal even after week 12. Conclusion: Using radiography, Monitoring the bone healing rate was done successfully. The BQE group showed the fastest healing, followed by BB, and QE groups.

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Radiographic Evaluation of Bone Healing Following Oral Administration of Bone Broth and Quail Eggs on Experimentally Drilled Femoral Bone Defect in Rabbits

Oviawe,

Fadasan,

Lawal

et al. 2023

Farm Anim. Health Nutr.

View full text Add to dashboard Cite

show abstract

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In Vivo Evaluation of The Novel Nanocomposite Porous 3D Scaffold in a Rabbit Model

Cited by 1 publication

References 26 publications

Radiographic Evaluation of Bone Healing Following Oral Administration of Bone Broth and Quail Eggs on Experimentally Drilled Femoral Bone Defect in Rabbits

Radiographic Evaluation of Bone Healing Following Oral Administration of Bone Broth and Quail Eggs on Experimentally Drilled Femoral Bone Defect in Rabbits

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