In-vivo heat retention comparison of eyelid warming masks

Bitton, Etty; Lacroix, Zoé; Léger, Stéphanie

doi:10.1016/j.clae.2016.04.002

Cited by 37 publications

(40 citation statements)

References 21 publications

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“…The upper outer eyelids may reach the peak temperature (40.1°C) after 2 min of treatment. Then, the heat may remain stable and decrease to 37.9°C after 12 min [16] Tichenor et al…”

Section: Warming and Humidity Devicesmentioning

confidence: 99%

Therapeutic Instruments Targeting Meibomian Gland Dysfunction

et al. 2020

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The most prevalent type of meibomian gland dysfunction (MGD), which is obstructive, is the main cause of evaporative dry eye and is characterized by changes in the meibum composition and duct obstruction. Eyelid hygiene has usually been the most common clinical approach. However, alternative therapies for MGD are emerging on the market. Some warming and humidity devices have led to an improvement in the signs and symptoms in MGD patients. Likewise, eyelid massaging and cleaning devices are also beneficial for ocular signs and symptoms; however, patients usually need more than one session to maintain the therapeutic effect. Thermal pulsation has been reported to be more efficient than other strategies, and the effects can last up to 12 months. Moreover, intense pulsed light therapy has been demonstrated to improve ocular signs and symptoms alone and in combination with other therapies. Proper counseling of clinicians considering MGD status and patient compliance will help patients to undergo the adequate technique that best suits their condition.

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“…The upper outer eyelids may reach the peak temperature (40.1°C) after 2 min of treatment. Then, the heat may remain stable and decrease to 37.9°C after 12 min [16] Tichenor et al…”

Section: Warming and Humidity Devicesmentioning

confidence: 99%

Therapeutic Instruments Targeting Meibomian Gland Dysfunction

et al. 2020

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“…14 Even commercially available eyelid masks microwaved for 10-20 s do not remain consistently above 38°C for the entire 10-min treatment. 14 An evaluation of eight methods of eyelid warming found that the method that most effectively maintained internal eyelid temperature, the bundle method, was also the most cumbersome. 15 Eyelid thermal pulsation devices apply heat at the appropriate temperature closer to the meibomian glands, while simultaneously compressing the glands to evacuate their contents.…”

Section: Introductionmentioning

confidence: 99%

<p>Comparison of the iLUX and the LipiFlow for the Treatment of Meibomian Gland Dysfunction and Symptoms: A Randomized Clinical Trial</p>

Tauber¹,

Owen

Bloomenstein³

et al. 2020

OPTH

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Purpose: To compare the effects of eyelid treatment with the iLUX MGD Treatment System and the LipiFlow Thermal Pulsation System on objective and subjective parameters of meibomian gland function and symptoms. Patients and Methods: In this randomized, open-label, controlled, multicenter clinical trial, both eyes of 142 patients aged ≥18 years with Ocular Surface Disease Index (OSDI) scores ≥23, total meibomian gland scores (MGS) ≤12 in the lower eyelid of each eye, and tear break-up time (TBUT) <10 s were randomized 1:1 to iLUX or LipiFlow treatment, with stratification by test center. The primary effectiveness endpoints were changes in total MGS (masked) and TBUT from baseline to 4 weeks. The secondary effectiveness endpoint was changed in OSDI score from baseline to 4 weeks. Results: Both devices significantly improved effectiveness outcomes, with no differences between the two devices. At the 4-week visit, mean MGS, TBUT, and OSDI scores improved at least 16.9 ± 11.5, 2.6 ± 3.2 s, and 28.0 ± 22.8, respectively, across treatment groups and treated eyes. Four device/procedure-related events occurred in the iLUX group, compared with none in the LipiFlow group, but there were no device-related adverse events that involved changes in lid margins, eyelids, or lash integrity. Corneal staining, intraocular pressure, and visual acuity did not differ in the two groups. Conclusion: Both treatments produced significant improvements in meibomian gland function and symptoms. For all effectiveness measures, there were no statistically significant differences between the two treatments.

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“…One reason was patients with conservative treatment used hot masks before complete chalazion resolution, and frequent and regular heating melted the meibum of the non-chalazion part, allowing the meibum to discharge on the eyelid margin. [21][22][23] Another reason was the improvement of meibomian gland function might differ between the two groups, because the size of chalazion was smaller in the conservative group, but chalazion size is often related to the pre-treatment duration in the clinic, not meibomian gland function. Moreover, hot compress is an effective method to improve meibomian gland function, 22 in this study, hot compresses was only used in conservative group.…”

Section: Discussionmentioning

confidence: 99%

Effects of chalazion and its treatments on the meibomian glands: a nonrandomized, prospective observation clinical study

Zhou

et al. 2020

Preprint

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Background To observe the effects of chalazion and its treatments on meibomian gland function and morphology in the chalazion area.Methods This nonrandomized, prospective observational clinical study included 58 patients (67 eyelids) who were cured of chalazion, including 23 patients (23 eyelids) treated with a conservative method and 35 patients (44 eyelids) treated with surgery. Infrared meibomian gland photography combined with image analysis by ImageJ software was used to measure the chalazion area proportion. Slit-lamp microscopy was employed to evaluate meibomian gland function, and a confocal microscope was used to observe meibomian gland acinar morphology before treatment and 1 month after complete chalazion resolution.Results At 1 month after chalazion resolution, the original chalazion area showed meibomian gland loss according to infrared meibomian gland photography in both groups. In patients who received conservative treatment, the meibomian gland function parameters before treatment were 0.74±0.75, 0.48±0.67, and 1.22±0.60, respectively. One month after chalazion resolution, the parameters were 0.35±0.49, 0.17±0.49, and 0.91±0.60, respectively; there was significant difference (P<0.05). The proportion of the chalazion area before treatment was 14.90 (11.03, 25.3), and the proportion of meibomian gland loss at 1 month after chalazion resolution was 14.64 (10.33, 25.77); there was no significant difference (P>0.05). In patients who underwent surgery, the meibomian gland function parameters before surgery were 0.93±0.87, 1.07±0.70, and 1.59±0.76, respectively, and at 1 month after chalazion resolution, they were 0.93±0.82, 0.95±0.75, and 1.52±0.70, respectively; there was no significant difference (P>0.05). The proportion of the chalazion area before surgery was 14.90 (12.04, 21.6), and the proportion of meibomian gland loss at 1 month after chalazion resolution was 14.84 (11.31, 21.81); there was no significant difference (P>0.05). The acinar structure could not be observed clearly in the meibomian gland loss area in most patients.Conclusions Chalazion causes meibomian gland loss, and the range of meibomian gland loss is not related to the treatment method but to the range of chalazion itself. A hot compress as part of conservative treatment can improve meibomian gland function at the site of chalazion in the short term.

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In-vivo heat retention comparison of eyelid warming masks

Cited by 37 publications

References 21 publications

Therapeutic Instruments Targeting Meibomian Gland Dysfunction

Therapeutic Instruments Targeting Meibomian Gland Dysfunction

<p>Comparison of the iLUX and the LipiFlow for the Treatment of Meibomian Gland Dysfunction and Symptoms: A Randomized Clinical Trial</p>

Effects of chalazion and its treatments on the meibomian glands: a nonrandomized, prospective observation clinical study

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