In vivo Investigation of the Removal of Trace Elements from Nucleic Acids of Yeast by Ionizing Radiation

Altmann, Hans; Stehlik, G.; Kaindl, K.

doi:10.1038/199823a0

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1964

1983

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Cited by 13 publications

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“…Investigations of the response of a DNA-Cu ++ complex to irradiation were initiated by in vivo experiments which showed that Cu ++ split off from DNA when yeast was irradiated (Altmann, Stehlik and Kaindl 1963). We performed experiments to demonstrate the effect of Cu ++ on the response of DNA to irradiation in vitro.…”

Section: Introductionmentioning

confidence: 99%

Gamma Irradiation of a DNA-Cu⁺⁺Complex

Höfer

Altmann

1971

International Journal of Radiation Biology and Related Studies

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Cu ++ in the DNA-Cu ++ complex is reduced to Cu + during irradiation. This Cu + is responsible for the increased stability of the complex and for the changes in the absorption spectra. The effects of radiation on the complex are those on DNA alone and those produced by Cu +. There is no difference in the radiation response of the DNA, as far as Tm values, absorption spectra and binding places for Cu + are concerned, whether Cu ++ is complexed to DNA or not.

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Section: Introductionmentioning

confidence: 99%