In vivo testing of nanoparticle-treated TTCP/DCPA-based ceramic surfaces

Chen, Wen Cheng; Ju, C.P.; Tien, Yin-Chun; Lin, Jinru

doi:10.1016/j.actbio.2008.12.002

Cited by 20 publications

(18 citation statements)

References 29 publications

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“…The use of OsteoSet Ò resulted in 8-35% new bone ingrowth in animal experiments [116,[120][121][122][123], which was found to be equivalent to autogenous and allogenic bone grafts [116]. However, in two studies no osteoconductive potential of OsteoSet Ò was noted [124,125]. No data on osteoconductive properties of Bone Plast Ò and Stimulan Ò was found.…”

Section: Biological Propertiesmentioning

confidence: 95%

Bone substitutes in the Netherlands – A systematic literature review

Stok¹,

Lieshout²,

El-Massoudi³

et al. 2011

Acta Biomaterialia

215

130

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Autologous bone grafting is currently considered as the gold standard to restore bone defects. However, clinical benefit is not guaranteed and there is an associated 8-39% complication rate. This has resulted in the development of alternative (synthetic) bone substitutes. The aim of this systematic literature review was to provide a comprehensive overview of literature data of bone substitutes registered in the Netherlands for use in trauma and orthopedic surgery. Brand names of selected products were used as search terms in three available databases: Embase, PubMed and Cochrane. Manuscripts written in English, German or Dutch that reported on structural, biological or biomechanical properties of the pure product or on its use in trauma and orthopedic surgery were included. The primary search resulted in 475 manuscripts from PubMed, 653 from Embase and 10 from Cochrane. Of these, 218 met the final inclusion criteria. Of each product, structural, biological and biomechanical characteristics as well as their clinical indications in trauma and orthopedic surgery are provided. All included products possess osteoconductive properties but differ in resorption time and biomechanical properties. They have been used for a wide range of clinical applications; however, the overall level of clinical evidence is low. The requirements of an optimal bone substitute are related to the size and location of the defect. Calcium phosphate grafts have been used for most trauma and orthopedic surgery procedures. Calcium sulphates were mainly used to restore bone defects after tumour resection surgery but offer minimal structural support. Bioactive glass remains a potential alternative; however, its use has only been studied to a limited extent.

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Section: Biological Propertiesmentioning

confidence: 95%

Bone substitutes in the Netherlands – A systematic literature review

Stok¹,

Lieshout²,

El-Massoudi³

et al. 2011

Acta Biomaterialia

215

130

View full text Add to dashboard Cite

show abstract

“…Treatment of nd-CPC with nanocrystallites on the surfaces of ceramic particles derived from c-CPC yields results different than those of non-treated c-CPC. 26,30 These results lead us to investigate the initial stage of nd-CPC setting in greater detail. Thus, the aim of the present study is to obtain the detailed reaction information on the newly developed nd-CPC.…”

Section: Introductionmentioning

confidence: 94%

Deriving fast setting properties of tetracalcium phosphate/dicalcium phosphate anhydrous bone cement with nanocrystallites on the reactant surfaces

Wang

Shih

Hung

et al. 2010

Journal of Dentistry

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“…The surgical procedures used have been described in our previous study. 28 Briefly, to implant the cement paste in the medial condyle, a longitudinal incision was made on the anterior surface of the femur. A ring was inserted at a depth of 5 mm to create a suitable drill depth.…”

Section: Procedures For In Vivo Testingmentioning

confidence: 99%