In vivo ultrasound-switchable fluorescence imaging using a camera-based system

Yu, Shaoming; Yao, Tingfeng; Liu, Yang; Yuan, Baohong

doi:10.1364/boe.385996

Cited by 9 publications

(11 citation statements)

References 31 publications

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“…New bioimaging technologies may benefit from ultrasound-switchable fluorescence (USF). 426 , 427 New insights and capabilities will likely emerge from such cross-disciplinary application of ultrasound-mediated effects.…”

Section: Discussionmentioning

confidence: 99%

“…New bioimaging technologies may benefit from ultrasound-switchable fluorescence (USF). 426,427 Chemical Reviews New insights and capabilities will likely emerge from such cross-disciplinary application of ultrasound-mediated effects. Second, individual ultrasound-responsive systems should be pushed to provide multiple functionalities in constrained applications.…”

Section: Discussionmentioning

confidence: 99%

“…In construction, ultrasound-induced self-healing of cements could support longer-lived smart cities. New bioimaging technologies may benefit from ultrasound-switchable fluorescence (USF). , New insights and capabilities will likely emerge from such cross-disciplinary application of ultrasound-mediated effects.…”

Section: Discussionmentioning

confidence: 99%

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Ultrasound-Responsive Systems as Components for Smart Materials

et al. 2021

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Smart materials can respond to stimuli and adapt their responses based on external cues from their environments. Such behavior requires a way to transport energy efficiently and then convert it for use in applications such as actuation, sensing, or signaling. Ultrasound can carry energy safely and with low losses through complex and opaque media. It can be localized to small regions of space and couple to systems over a wide range of time scales. However, the same characteristics that allow ultrasound to propagate efficiently through materials make it difficult to convert acoustic energy into other useful forms. Recent work across diverse fields has begun to address this challenge, demonstrating ultrasonic effects that provide control over physical and chemical systems with surprisingly high specificity. Here, we review recent progress in ultrasound–matter interactions, focusing on effects that can be incorporated as components in smart materials. These techniques build on fundamental phenomena such as cavitation, microstreaming, scattering, and acoustic radiation forces to enable capabilities such as actuation, sensing, payload delivery, and the initiation of chemical or biological processes. The diversity of emerging techniques holds great promise for a wide range of smart capabilities supported by ultrasound and poses interesting questions for further investigations.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Ultrasound-Responsive Systems as Components for Smart Materials

et al. 2021

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“…A study designed the USF contrast agents (ICG-NPs and ExiTron nano 12000) with particle sizes ranging from 70 nm to 330 nm and administered themintravenously to understand the distribution of contrast agents in tumor and normal tissues including liver, kidney, and spleen. Comparatively, ICG-NPs in the mice’s tumors and organsexhibited higher bio-stability, mostly in the liver and spleen, which were used for imaging in vivo [ 170 ].…”

Section: Nanomaterials and Their Clinical Applicationmentioning

confidence: 99%

Broad-Spectrum Theranostics and Biomedical Application of Functionalized Nanomaterials

Alshamrani

2022

Polymers

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Nanotechnology is an important branch of science in therapies known as “nanomedicine” and is the junction of various fields such as material science, chemistry, biology, physics, and optics. Nanomaterials are in the range between 1 and 100 nm in size and provide a large surface area to volume ratio; thus, they can be used for various diseases, including cardiovascular diseases, cancer, bacterial infections, and diabetes. Nanoparticles play a crucial role in therapy as they can enhance the accumulation and release of pharmacological agents, improve targeted delivery and ultimately decrease the intensity of drug side effects. In this review, we discussthe types of nanomaterials that have various biomedical applications. Biomolecules that are often conjugated with nanoparticles are proteins, peptides, DNA, and lipids, which can enhance biocompatibility, stability, and solubility. In this review, we focus on bioconjugation and nanoparticles and also discuss different types of nanoparticles including micelles, liposomes, carbon nanotubes, nanospheres, dendrimers, quantum dots, and metallic nanoparticles and their crucial role in various diseases and clinical applications. Additionally, we review the use of nanomaterials for bio-imaging, drug delivery, biosensing tissue engineering, medical devices, and immunoassays. Understandingthe characteristics and properties of nanoparticles and their interactions with the biological system can help us to develop novel strategies for the treatment, prevention, and diagnosis of many diseases including cancer, pulmonary diseases, etc. In this present review, the importance of various kinds of nanoparticles and their biomedical applications are discussed in much detail.

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“…In 2020, Yu et al. [ 52 ] successfully obtained in vivo UCF images of the glioblastoma tumor by combining this ICCD camera-based imaging system and ICG-PNIPAM NPs with a particle size of approximately 330 nm. In particular, the 3D micro-mesoscopic information of lesion tissue was well presented.…”

Section: Advances In Nir-ucf Imaging Systemsmentioning

confidence: 99%