Urinary stone disease is increasingly prevalent, with a lifetime risk of about 12% in men and 6% in women. 1 Age of onset of a first stone episode for men rises from their 20s and peaks at age 40-60 years, with an incidence of three cases per 1000 population per year. Women appear to peak a little younger in their late 20s. The male to female ratio is narrowing, with one study showing a reduction from 1.7:1 to 1.3:1 over a five year period. 2 Presentation varies according to geographical and seasonal factors, with higher incidences in warmer climates and during the summer months. 3This review includes the latest information from meta-analyses, systematic reviews, randomised trials, current guidelines, and other peer reviewed evidence to provide a background on presentation, investigation, and medical and surgical management of patients with renal colic.
What are urinary stones?Urinary stones are formed by the aggregation of crystals with a non-crystalline protein (matrix) component. 3 These crystals clump together to form a stone and then move when they reach a certain size and pass down the ureter, frequently causing colic symptoms. Eighty per cent of stones contain calcium, most commonly in the form of calcium oxalate (60%). Calcium phosphate accounts for 20% of stones, with uric acid forming approximately 7%, 3 although this uric acid proportion may rise in obese patients. Another 7% are infection stones containing magnesium ammonium phosphate. Bladder stones usually have a different cause, often as a result of bladder outflow obstruction.