2023
DOI: 10.1002/rcm.9507
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Inadequate definition of the limit of quantification used for the analysis of perfluoroalkyl substances in food by liquid chromatography–tandem mass spectrometry may compromise the reliability of the data requested by the European regulation

Abstract: Liquid chromatography–tandem mass spectrometry (LC–MS/MS) is a widespread technology used for the quantitative determination of per‐ and polyfluoroalkyl substances (PFAS) in foodstuff. Specifically, LC–MS/MS offers an attractive performance by combining the sensitivity and selectivity required by the European Union for testing perfluorooctane sulfonic acid, perfluorooctanoic acid, perfluorononanoic acid, and perfluorohexane sulfonic acid with maximum limits of quantification (LOQ) in the sub‐parts‐per‐billion … Show more

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