Inception and Dynamics of Traveling-Bubble-Type Cavitation in a Venturi.

Sato, Keiichi; Hachino, Kouji; Saito, Yasuhiro

doi:10.1299/kikaib.70.69

Cited by 6 publications

(3 citation statements)

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“…These bubbles, or cavitation nuclei, can be exogenously delivered (this will be discussed in a subsequent section), or as more prominently explored in the SDT field, generated from a driving acoustic pulse within biological fluids. These cavitation nuclei typically are located at the boundary of a fluid and within gas filled crevices, such as the cellular cytoplasm. The existence of these nuclei has been extensively researched and confirmed, while the mechanism behind their creation and stabilization continue to be explored. , Nevertheless, the field of SDT predominantly assumes that cavitation leading to sonosensitizer activation arises from the de novo formation of endogenous microbubbles in response to a driving acoustic pressure wave.…”

Section: Mechanisms Governing Sonodynamic Therapymentioning

confidence: 99%

Activating Drugs with Sound: Mechanisms Behind Sonodynamic Therapy and the Role of Nanomedicine

2020

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Sonodynamic therapy (SDT) is a promising therapeutic platform for minimally invasive cancer treatment in which acoustically susceptible drug agents, sonosensitizers, are activated by deep-tissue-penetrating low frequency ultrasound. Despite growing research in recent years, the field has yet to clearly elucidate broadly applicable mechanisms by which acoustic cavitation triggers sonosensitizer therapeutic activity, creating difficulties in achieving substantial and translatable therapeutic efficacy. In this review, we will critically analyze the proposed mechanisms underlying SDT and overview how nanomedicines can complement and extend these mechanisms to deliver more efficacious SDT. In doing so, we aim to highlight potential avenues toward viable implementation of SDT as a cancer therapy.

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Section: Mechanisms Governing Sonodynamic Therapymentioning

confidence: 99%

Activating Drugs with Sound: Mechanisms Behind Sonodynamic Therapy and the Role of Nanomedicine

2020

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“…The present cavitation knowledge (experimental and analytical) has contributed immensely towards improving the design of rudimentary conventional scale fluid machinery like hydrofoils [17,18], valves [18][19][20][21][22], orifices [20][21][22][23][24][25][26][27][28][29][30] and venturis [31][32][33][34][35][36][37][38][39][40]. Mishra and Peles [41][42][43][44][45] in several recent publications have extended this research endeavor to study hydrodynamic cavitation in micro systems.…”

Section: Introductionmentioning

confidence: 99%

Hydrodynamic cavitation and boiling in refrigerant (R-123) flow inside microchannels

Schneider

Koşar

Peles

2007

International Journal of Heat and Mass Transfer

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“…Further, Li et al [15] investigated the impact of various geometric parameters on cavitation inception using a numerical simulation and experimental methods and discovered that flow resistance determines cavitation inception. Sato et al [16] used a high-speed video camera to visualize the behavior of a moving bubble cavitation in a Venturi from the inception to collapse process. Brunhart et al [17] verified two mechanisms of vapor shedding (re-entrant jet and condensation shock) and offered more information on vapor shedding using the computational fluid dynamics (CFDs) method.…”

Section: Introductionmentioning

confidence: 99%

Numerical Investigation of the Cavitation Characteristics in Venturi Tubes: The Role of Converging and Diverging Sections

Liu

2023

Applied Sciences

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Cavitation is a typical physical process that has shown to be highly valuable in the wastewater treatment field. This study aims to investigate the effects of the converging and diverging sections of a Venturi tube on the cavitation flow field. Multiphase flows in tubes are presented using the mixture model and the standard k-ε model. And the Schnerr and Sauer cavitation model is employed to simulate the vapor–liquid phase transition process. Both grid independence and the numerical method’s feasibility were validated before the research. The results showed that the influence of the divergence section length on Venturi cavitation characteristics depends on the provided pressure conditions. As the pressure increases, shorter divergence sections result in more significant cavitation effects. The length of the convergence section displays various cavitation behaviors under different pressure situations. A small contraction section length can achieve better cavitation effects in high-pressure applications, whereas the opposite is true in low-pressure cases. Within the scope of this study, it was observed that the Venturi tube with a divergent section of 14 Lt and a convergent one of 2.4 Lt provided enhanced cavitation performance when subjected to inlet pressures ranging from 0.8 to 1.2 MPa. Our findings indicate that the selection of converging and diverging section lengths in Venturi tubes should consider the corresponding operational pressure conditions, which provides valuable guidance and engineering significance in the research and development of Venturi cavitation devices in hydraulic engineering.

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Inception and Dynamics of Traveling-Bubble-Type Cavitation in a Venturi.

Cited by 6 publications

References 0 publications

Activating Drugs with Sound: Mechanisms Behind Sonodynamic Therapy and the Role of Nanomedicine

Activating Drugs with Sound: Mechanisms Behind Sonodynamic Therapy and the Role of Nanomedicine

Hydrodynamic cavitation and boiling in refrigerant (R-123) flow inside microchannels

Numerical Investigation of the Cavitation Characteristics in Venturi Tubes: The Role of Converging and Diverging Sections

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