Incessant ventricular tachycardia due to multiple cardiac rhabdomyomas in an infant with Tuberous Sclerosis

Abstract

We report a case of incessant ventricular tachycardia managed successfully with medications. The transthoracic echocardiogram showed multiple cardiac rhabdomyomas involving ventricular free wall and outflow tracts. Computerized tomography of brain showed multiple subependymal tubers confirming Tuberous Sclerosis. The follow up assessment showed sinus rhythm and regressing cardiac rhabdomyomas.

Cardiovascular Manifestations of Tuberous Sclerosis Complex and Summary of the Revised Diagnostic Criteria and Surveillance and Management Recommendations From the International Tuberous Sclerosis Consensus Group

“…Tachycardia mechanisms have been related to atrial, accessory AV connection reentrant, and ventricular tachycardia. [38][39][40][41][42] Ventricular preexcitation associated with abnormal AV connections has also been commonly reported and has been noted to participate in rapid potentially lifethreatening anomalous AV conduction during atrial fibrillation. [43][44][45] The mechanisms of arrhythmia have often been directly linked to the location of specific cardiac rhabdomyomas.…”

Giant Cardiac Rhabdomyoma with Mixed Atrial Tachycardia and Nonsustained Ventricular Tachycardia in a Newborn with Tuberous Sclerosis

“…Previous study reported that atrial and/or ventricular ectopic beats were seen in 24% of neonates and infants. And other critical arrhythmias, such as pre-excitation syndrome, refractory ectopic AT and incessant VT were demonstrated in cardiac rhabdomyomas [1,7,8]. In the case, nonsustained VT was intermittently observed.…”

ECG pattern of myocardial infarction in a child of the first month of life with multiple heart rhabdomyomas (clinical case)

“…Частыми находками являются различные нарушения ритма сердца, определяемые локализацией рабдомиом. При холтеровском мониторировании ЭКГ часто регистрируются различные нарушения ритма и проводимости сердца: синдром Вольфа -Паркинсона -Уайта, наджелудочковая тахикардия, синдром слабости синусного узла, желудочковая тахикардия [9,10]. По данным литературы, при рабдомиомах сердца часто описываются аномалии ЭКГ.…”