Incidence among men of asymptomatic abdominal aortic aneurysms: estimates from 500 screen detected cases

Vardulaki, Katerina; Prevost, Teresa C.; Walker, Neil M.; Day, Nicholas E.; Wilmink, A; Quick, Clive R.G.; Ashton, H. A.; Scott, R. A. P.

doi:10.1136/jms.6.1.50

Cited by 75 publications

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“…A similar incidence was found in England, 2 in the Veteran Affairs Cooperative Study in the United States, 5 and in the Chichester study. 20 A lower incidence of AAA was found in an Asian population.…”

Section: Discussionsupporting

confidence: 77%

“…Ruptured AAA is the cause of 1% to 2% of all deaths in the Western world. 1, 2 The incidence of AAA may have increased during the past 2 decades. 3 This can be explained in part by longer life expectancy in the general population and by the fact that some AAAs have been diagnosed and treated owing to the introduction of screening programs and improved diagnostic tools.…”

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confidence: 99%

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Risk Factors for Abdominal Aortic Aneurysms

et al. 2009

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Section: Discussionsupporting

confidence: 77%

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confidence: 99%

Risk Factors for Abdominal Aortic Aneurysms

et al. 2009

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“…The prevalence of asymptomatic AAA in men is between 5% and 10%. 28 The patients included in this meta-analysis were selected because they were symptomatic and therefore underwent sonography and CT scan. From the prevalence data of AAA, we feel that all patients with abdominal or flank pain age 50 years or older should be screened for AAA in the ED.…”

Section: Discussionmentioning

confidence: 99%

Systematic Review: Emergency Department Bedside Ultrasonography for Diagnosing Suspected Abdominal Aortic Aneurysm

Rubano

Mehta

Caputo

et al. 2013

Academic Emergency Medicine

133

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“…Scott et al, 1995 reported in men and women aged 65-80 years a prevalence rate of 4 % overall and 7.6 % of men. Vardulaki et al, 1999 observed in two different areas the prevalence of AAA ranging between 5.3 % and 8% and between 6.18% and 9.88 %, respectively, in men aged between 65 and 79 years. In the Multicentre Aneurysm Screening Study (MASS) the prevalence in men aged 65-74 years was 4.9% (Ashton et al, 2002).…”

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confidence: 88%

“…This does not mean that these subjects will die of a ruptured aneurysm. Vardulaki et al, 1999 estimated the prevalence of AAA reaching around 10 % of the population at an age of 74 years, nevertheless in the year 1997 ruptured AAA caused not more than approximately 2.1 % of all deaths in men and 0.75 % of all deaths in women over the age of 65 in England and Wales. These data have not changed in the last 10 years; on the contrary, the mortality rate might be even decreasing.…”

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confidence: 99%

The Abdominal Aortic Aneurysm – Prognosis, Treatment, Screening and Cost-Effectiveness

Grundmann¹

2011

Diagnosis, Screening and Treatment of Abdominal, Thoracoabdominal and Thoracic Aortic Aneurysms

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Prevalence of abdominal aortic aneurysm and mortality rateGenerally, an AAA is considered to be present when the minimum anterioposterior diameter of the aorta reaches 3.0 cm (Hirsch et al., 2006). The prevalence of AAA depends on various risk factors, as advancing age, family history, male gender, and tobacco use. According to the ACC/AHA guidelines (Hirsch et al., 2006) the prevalence of AAA 2.9 to 4.9 cm in diameter ranges from 1.3 % for men aged 45 to 54 years up to 12.5 % for men 75 to 84 years of age. Comparable prevalence figures for women are 0% and 5.2 %, respectively. Scott et al., 1995 reported in men and women aged 65-80 years a prevalence rate of 4 % overall and 7.6 % of men. Vardulaki et al., 1999 observed in two different areas the prevalence of AAA ranging between 5.3 % and 8% and between 6.18% and 9.88 %, respectively, in men aged between 65 and 79 years. In the Multicentre Aneurysm Screening Study (MASS) the prevalence in men aged 65-74 years was 4.9% (Ashton et al., 2002). In these studies the AAA was defined as an aortic diameter  3cm. If clinically important aneurysms are only taken into account (AAA www.intechopen.com Diagnosis, Screening and Treatment of Abdominal, Thoracoabdominal and Thoracic Aortic Aneurysms 2 measuring  4 cm in diameter) the indicated prevalence would be lower. Van Walraven et al., 2010 identified the prevalence of incidental AAA during imaging for other reasons. In 79,121 abdominal images 812 incidental AAA with a mean diameter of 4.0 cm (1% of all studies) were detected in patients with a mean age of 74 years. Lederle et al., 1997 reported the results of ultrasonography screening for AAA in 73,451 US veterans who were 50 to 79 years of age and had no history of AAA. The infrarenal aortic diameter was at least 4 cm in 1031 patients (1.4%), 368 patients (0.5%) had an AAA of 5 cm or larger. Smoking was the factor most closely associated with AAA in this study. In men who never smoked the prevalence of AAA 4 cm or larger was 0 % (patient age 50 to 59 years) and 0.8% (patient age > 75 years), respectively. The corresponding figures for men who smoked were 0.9 % and 2.7 %, respectively. A second cohort study of the Department of Veterans Affairs medical centers (Lederle et al., 2000) including 52,745 subjects aged 50 to 79 years confirmed the findings previously reported and supported the hypothesis that AAA is primarily a smoking-related disease. In this study AAA of 4.0 cm or larger were detected in 613 participants (1.2%). The excess prevalence associated with smoking accounted for approximately 75% of all AAA of 4.0 cm or larger. Smoking as a very strong risk factor for AAA was also proven by the Tromsø study (Forsdahl et al., 2009). When subjects who reported to have never been a daily smoker were compared with those who currently were smoking 20 cigarettes or more, the latter group had a > 13 times increased risk of an incident AAA during follow-up. In the women`s health initiative, an observational study involving 161,808 postmenopausal women, too, a strong positi...

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Incidence among men of asymptomatic abdominal aortic aneurysms: estimates from 500 screen detected cases

Abstract: Hypotheses are offered to explain this unexpected early peak in incidence. This information should allow the definition of the optimum age for screening, and the relative benefits of screening at different intervals if widespread screening is adopted in the future.

Cited by 75 publications

References 8 publications

Risk Factors for Abdominal Aortic Aneurysms

Risk Factors for Abdominal Aortic Aneurysms

Systematic Review: Emergency Department Bedside Ultrasonography for Diagnosing Suspected Abdominal Aortic Aneurysm

The Abdominal Aortic Aneurysm – Prognosis, Treatment, Screening and Cost-Effectiveness

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