Incidence and Characteristics of Ventilator-Associated Events Reported to the National Healthcare Safety Network in 2014*

Magill, Shelley S.; Li, Qunna; Gross, Cindy; Dudeck, Margaret A.; Allen-Bridson, Katherine; Edwards, Jonathan R.

doi:10.1097/ccm.0000000000001871

Cited by 61 publications

(71 citation statements)

References 26 publications

(34 reference statements)

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“…5 Although VAE reporting is not mandated, 36 BICUs reported data to the NHSN in 2014 with a pooled mean incidence of 6.55 VAE/1,000 ventilator days and a pooled mean incidence of IVACs (including possible VAP) of 2.93 events/1,000 ventilator days. 6 We found an incidence of VAE-possible VAP cases ranging from 0.6 to 1.0/1,000 ventilator days over a 4.5-year period, which was much lower than our pre-2013 VAP rates. Even though the BICU is our highest risk unit for VAP, we found very few events that met the current VAE-possible VAP definition.…”

Section: Discussioncontrasting

confidence: 63%

From VAP to VAE: Implications of the New CDC Definitions on a Burn Intensive Care Unit Population

Lachiewicz

Weber

Duin

et al. 2017

Infect. Control Hosp. Epidemiol.

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Section: Discussioncontrasting

confidence: 63%

From VAP to VAE: Implications of the New CDC Definitions on a Burn Intensive Care Unit Population

Lachiewicz

Weber

Duin

et al. 2017

Infect. Control Hosp. Epidemiol.

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“…Edwards et al [7] found that VAP prevalence in PICUs in the USA was 0%-3.2% in both 2006 and 2007. Magill et al [4] reported that VAP prevalence was 6.89-8.79 patients per 1,000 ventilator days. In Turkey, the National Surveillance report of 2015 estimated VAP prevalence in PICUs as 4.7 patients per 1,000 ventilator days [8].…”

Section: Discussionmentioning

confidence: 99%

“…Prior antibiotic use, application of invasive procedures, use of drugs affecting gastric empty-ing and pH, aspiration of gastric contents, prolonged mechanical ventilation, patient position, severity of underlying illness; central nervous system disorders, frequent changes of endotracheal tubes, and presence of coma, pneumonia, and acute respiratory distress syndrome are among the factors predicting VAP development [3]. VAP is an important cause of morbidity and mortality in patients in the ICU [4].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Microorganisms Causing Ventilator-Associated Pneumonia in a Pediatric Intensive Care Unit

et al. 2017

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Objective: The aim of this study was to identify microorganisms causing ventilator-associated pneumonia (VAP) and also study the antibiotic resistance/susceptibility. Materials and Methods:We retrospectively assessed microorganisms isolated from patients diagnosed with VAP in a pediatric intensive care unit between January 1, 2014, and June 30, 2016. Results:We included 44 patients diagnosed with VAP. The prevalence thereof was 8.6 patients per 1,000 ventilator days. Mechanical ventilation was required for 56.5% of patients. Thirty-three patients (75%) died. An underlying chronic disease was detected in 75% of patients (n=33). Fifty microorganisms were isolated from 44 patients. Single microorganisms were isolated from 86.4% (n=38) and two from 13.6% (n=6) of patients. Of all the isolated bacteria, 96% (n=48) were gram-negative; the most common was Pseudomonas aeruginosa (32%), followed by Klebsiella pneumoniae (24%) and Acinetobacter baumannii (22%). The isolates were most susceptible to colistin (92.6%), followed by piperacillin-tazobactam (71.4%), amikacin (65.2%), and gentamicin (52.2%). No enterobacterium or Acinetobacter strain was resistant to colistin; however, 13% of P. aeruginosa isolates were resistant. Conclusion:In VAP, it is essential to catalog antibiotic resistance patterns of bacteria present in the unit to ensure that empirical antibiotic therapy is effective.Keywords: Ventilator-associated pneumonia, pediatric intensive care, microorganism, antibiotic Bulgular: Çalışmaya VİP tanısı alan 44 hasta alındı. VİP hızı 1000 ventilatör gününde 8,6 olarak saptandı. Mekanik ventilatör kullanım oranı %56,5 idi. VİP tanısı alan olguların %75 (n=33)'nin öldüğü saptandı. VİP tanısı alan hastaların %75 (n=33)'inde altta yatan kronik hastalık tespit edildi. VİP tespit edilen 44 olguda 50 mikroorganizma izole edildi. Olguların %86,4'nda (n=38) tek mikroorganizma, %13.6 (n=6)'nda iki mikroorganizma etken olarak izole edildi. İzole edilen suşların %96' sının (n=48) gram negatif bakteri olduğu saptandı. Çalış-mamızda en sık izole edilen gram negatif ajan Pseudomonas Aeruginosa (%32) iken bunu Klebsiella pneumonia (%24) ve Acinetobacter baumannii (%22) izlemekte idi. Genel antibiyotik duyarlılığı incelendiğinde mikroorganizmaların en hassas olduğu antibiyotikler sırasıyla Kolistin (%92,6), Piperasilin-tazobaktam (% 71,4), Amikasin (%65,2) ve Gentamisin (%52,2) olarak saptandı. Enterobacteriaceae ve Acinetobacter suşlarında Kolistin direnci görülmezken P. aeruginosa izolatlarında, kolistin direnci %13 olarak saptandı.Sonuç: Ventilatör ilişkili pnömonidee, etkili ampirik antibiyotik tedavisi için her ünitenin kendi florasının direnç özelliklerini bilmesi gerekmektedir.Anahtar Kelimeler: Ventilatör ilişkili pnömoni, çocuk yoğun bakım, mikroorganizma, antibiyotik Eurasian J Med

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“…Ventilator‐associated pneumonia (VAP) is the most common severe infectious complication of mechanical ventilation; reported incidences range from 1·2 to 18·3 episodes per 1000 days of mechanical ventilation, varying depending on the study population, the definition used for the diagnosis (Magill et al, ; Skrupky et al, ) and the preventive measures applied in the reporting intensive care unit (ICU) (Álvarez Lerma et al, ; Sinuff et al, ). Likewise, the mortality attributable to VAP varies widely, initially ranging from 33% to 50%, although recent studies have reported much lower values, ranging from 6% to 13% (Melsen et al, ; Melsen et al, ; Timsit et al, ).…”

Section: Introductionmentioning

confidence: 99%

Nursing workload and compliance with non‐pharmacological measures to prevent ventilator‐associated pneumonia: a multicentre study

Jam

Mesquida

Hernández³

et al. 2018

Nursing in Critical Care

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Most critical care nurses have good baseline knowledge of non-pharmacological measures to prevent ventilator-associated pneumonia. Failure to comply with these measures is probably more related with behavioural, structural and organizational aspects than with nursing workload. Interventions to improve compliance might be more effective if they focus on factors such as work climate and professionals' attitudes.

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Incidence and Characteristics of Ventilator-Associated Events Reported to the National Healthcare Safety Network in 2014*

Abstract: Supplemental Digital Content is available in the text.

Cited by 61 publications

References 26 publications

From VAP to VAE: Implications of the New CDC Definitions on a Burn Intensive Care Unit Population

From VAP to VAE: Implications of the New CDC Definitions on a Burn Intensive Care Unit Population

Evaluation of Microorganisms Causing Ventilator-Associated Pneumonia in a Pediatric Intensive Care Unit

Nursing workload and compliance with non‐pharmacological measures to prevent ventilator‐associated pneumonia: a multicentre study

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