Mesotheliomas are rare neoplasms of the pleura, peritoneum or pericardium, which are frequently associated with exposure to asbestos. Early diagnosis and establishment of a standard treatment for malignant peritoneal mesothelioma is difficult. We report on a case of malignant peritoneal mesothelioma in a 53-year-old woman with no history of exposure to asbestos or previous radiotherapy.Keywords: Malignant mesothelioma; Peritoneum; Chemotherapy CASE REPORT Received: 2012.6.18. Revised: 2012.8.25. Accepted: 2012.17. Corresponding author: Sung Ook Hwang, MD Department of Obstetrics and Gynecology, Inha University College of Medicine, 27 Inhang-ro, Jung-gu, Incheon 400-711, Korea Tel: +82-32-890-2270 Fax: +82-32-890-2274 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/ by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright © 2012. Korean Society of Obstetrics and GynecologyKorean J Obstet Gynecol 2012;55(11):865-869 http://dx.doi.org/10.5468/ KJOG.2012.55.11.865 pISSN 2233-5188 · eISSN 2233 In the United States, mesothelioma, a rare cancer, is estimated to occur in approximately 2,500 people annually [1]. Sporadic cases have been reported in Korea. Although, malignant pleural mesothelioma is the most common type of mesothelioma, mesothelioma has also observed in the peritoneum and pericardium. Malignant pleural mesothelioma is observed mainly in older men (median age, 72 years) who have been exposed to asbestos, although it occurs decades after exposure (20 to 40 years later) [2]. Most cases of mesothelioma have been linked to asbestos exposure, however, some reports have suggested that radiotherapy may also be a cause of mesothelioma [3,4]. Reports of malignant peritoneal mesotheliomas in women are rare. The significant variation in incidence may reflect erroneous diagnosis of peritoneal serous carcinomas or well-differentiated papillary mesotheliomas as malignant peritoneal mesothelioma. Frequency of exposure of asbestos in patients with malignant peritoneal mesothelioma ranges from 0 to 50% [5]. Malignant peritoneal mesotheliomas are most commonly diagnosed during the fifth to seventh decades of life [6]. We report on a case of malignant peritoneal mesothelioma in a 53-year-old woman with no history of exposure to asbestos or previous radiotherapy, along with a brief review of the literature.
Case ReportA 53-year-old woman was transferred to our hospital in September 2010, complaining of fever and right flank pain. She was in good health and other than being a housewife, she had no history of employment. Abdomino-pelvic computed tomography (CT) revealed a lobulated contoured heterogeneously enhancing mass, which measured 7.5 × 5.2 × 9.5 cm, in the right subhepatic space and multiple small nodular lesions with fatty infiltration in mesentery and omentum (Fig. 1). 18-fluorodeoxyglucose positron emission ...