Incidence and Factors associated with Mental Health Disorders in Rectal Cancer Patients Post-Restorative Proctectomy

Moon, Jeongyoon; Garfinkle, Richard; Zelkowitz, Phyllis; Dell’Aniello, Sophie; Vasilevsky, Carol‐Ann; Brassard, Paul; Boutros, Marylise

doi:10.1097/dcr.0000000000002744

Cited by 4 publications

(1 citation statement)

References 39 publications

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“…In this issue, 2 articles address this important subject. The first by Moon et al 5 describes a 32% rate of incident mental health disorders in patients without known prior mental health problems who had undergone a restorative proctectomy for cancer. We acknowledge bowel dysfunction in these patients but do not realize how this impacts other facets of their lives.…”

Section: Ensure Healthy Lives and Promote Well-being For All At All Agesmentioning

confidence: 99%

Sustainable Development Goals: Halfway There?

Galandiuk

2023

Diseases of the Colon &Amp; Rectum

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Section: Ensure Healthy Lives and Promote Well-being For All At All Agesmentioning

confidence: 99%

Sustainable Development Goals: Halfway There?

Galandiuk

2023

Diseases of the Colon &Amp; Rectum

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Effect of a Mobile Health–Based Remote Interaction Management Intervention on the Quality of Life and Self-Management Behavior of Patients With Low Anterior Resection Syndrome: Randomized Controlled Trial

Zhou,

Li,

Pang

et al. 2024

J Med Internet Res

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Background: People who undergo sphincter-preserving surgery have high rates of anorectal functional disturbances, known as low anterior resection syndrome (LARS). LARS negatively affects patients' quality of life (QoL) and increases their need for self-management behaviors. A high level of self-management behavior effectively improved the impact of LARS on patients. Therefore, approaches to enhance self-management behavior and QoL are vital.Objective: This study aimed to assess the effectiveness of a remote interactive management intervention designed to enhance the QoL and self-management behavior of patients with LARS.Methods: From July 2022 to May 2023, we conducted a single-blinded randomized controlled trial (RCT) and recruited 120 patients with LARS in a tertiary hospital in Hefei, China. All participants were randomly assigned to the intervention group (using the 'e-bowel safety' applet and monthly Motivational interviewing) or the control group (usual care and an information booklet). Our team provided a 3-month intervention and followed up with all participants for an additional 3 months. The primary outcome was patient QoL measured using the European Organization for Research and Treatment of Cancer quality of life questionnaire core 30 (EORTC-QLQ-C30). The secondary outcomes were evaluated using the Bowel Symptoms Selfmanagement Behaviors Questionnaire (BSSBQ), LARS Score, and Perceived Social Support Scale (PSSS). Data collection occurred at study enrollment, the end of the three-month intervention, and the three-month follow-up. Results:In the end, 111 participants completed the study. In the intervention group, 5 participants withdrew; 4 participants withdrew in the control group. Compared with the participants in the control group, those in the intervention group had significantly larger improvements in the EORTC-QLQ-C30 total score (mean difference 11.51, 95% CI 10.68-12.35, Cohen's d=1.73) and BSSBQ total score (mean difference 8.80, 95% CI 8.28-9.32, Cohen's d=1.94) after intervention, and this improvement effect remained stable at 3-month follow-up (mean difference 14.47, 95% CI 13.65-15.30, Cohen's d=1.58), (mean difference 8.85, 95% CI 8. Cohen's d=2.23). The LARS Score total score had significantly larger decreases after intervention (mean difference -3.28, 95% CI -4.03 to -2.54, Cohen's d=-0.39) and at 3-month follow-up (mean difference -6.69, 95% CI -7.45 to -5.93, Cohen's d=-0.69). The PSSS total score had significantly larger improvements after intervention (mean difference 0.47, 95% CI 0.22-0.71, Cohen's d=1.81); however, this effect did not persist at 3-month follow-up (mean difference 0.23, 95% CI -0.20 to 0.45; P=0.074).

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Effect of a Mobile Health–Based Remote Interaction Management Intervention on the Quality of Life and Self-Management Behavior of Patients With Low Anterior Resection Syndrome: Randomized Controlled Trial (Preprint)

Zhou,

Li,

Pang

et al. 2023

Preprint

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BACKGROUND People who undergo sphincter-preserving surgery have high rates of anorectal functional disturbances, known as low anterior resection syndrome (LARS). LARS negatively affects patients’ quality of life (QoL) and increases their need for self-management behaviors. Therefore, approaches to enhance self-management behavior and QoL are vital. OBJECTIVE This study aims to assess the effectiveness of a remote digital management intervention designed to enhance the QoL and self-management behavior of patients with LARS. METHODS From July 2022 to May 2023, we conducted a single-blinded randomized controlled trial and recruited 120 patients with LARS in a tertiary hospital in Hefei, China. All patients were randomly assigned to the intervention group (using the “e-bowel safety” applet and monthly motivational interviewing) or the control group (usual care and an information booklet). Our team provided a 3-month intervention and followed up with all patients for an additional 3 months. The primary outcome was patient QoL measured using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30. The secondary outcomes were evaluated using the Bowel Symptoms Self-Management Behaviors Questionnaire, LARS score, and Perceived Social Support Scale. Data collection occurred at study enrollment, the end of the 3-month intervention, and the 3-month follow-up. Generalized estimating equations were used to analyze changes in all outcome variables. RESULTS In the end, 111 patients completed the study. In the intervention group, 5 patients withdrew; 4 patients withdrew in the control group. Patients in the intervention group had significantly larger improvements in the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 total score (mean difference 11.51; 95% CI 10.68-12.35; Cohen d=1.73) and Bowel Symptoms Self-Management Behaviors Questionnaire total score (mean difference 8.80; 95% CI 8.28-9.32; Cohen d=1.94) than those in the control group. This improvement effect remained stable at 3-month follow-up (mean difference 14.47; 95% CI 13.65-15.30; Cohen d=1.58 and mean difference 8.85; 95% CI 8.25-9.42; Cohen d=2.23). The LARS score total score had significantly larger decreases after intervention (mean difference –3.28; 95% CI –4.03 to –2.54; Cohen d=–0.39) and at 3-month follow-up (mean difference –6.69; 95% CI –7.45 to –5.93; Cohen d=–0.69). The Perceived Social Support Scale total score had significantly larger improvements after intervention (mean difference 0.47; 95% CI 0.22-0.71; Cohen d=1.81). CONCLUSIONS Our preliminary findings suggest that the mobile health–based remote interaction management intervention significantly enhanced the self-management behaviors and QoL of patients with LARS, and the effect was sustained. Mobile health–based remote interventions become an effective method to improve health outcomes for many patients with LARS. CLINICALTRIAL Chinese Clinical Trial Registry ChiCTR2200061317; https://tinyurl.com/tmmvpq3

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Incidence and Factors associated with Mental Health Disorders in Rectal Cancer Patients Post-Restorative Proctectomy

Cited by 4 publications

References 39 publications

Sustainable Development Goals: Halfway There?

Sustainable Development Goals: Halfway There?

Effect of a Mobile Health–Based Remote Interaction Management Intervention on the Quality of Life and Self-Management Behavior of Patients With Low Anterior Resection Syndrome: Randomized Controlled Trial

Effect of a Mobile Health–Based Remote Interaction Management Intervention on the Quality of Life and Self-Management Behavior of Patients With Low Anterior Resection Syndrome: Randomized Controlled Trial (Preprint)

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