Incidence and maternal-fetal risk factors of stillbirth: A population-based historical cohort and a nested case-control study

Maleki, Zahra; Ghaem, Haleh; Seif, Mozhgan; Foruhari, Sedigheh

doi:10.21203/rs.2.18523/v1

Cited by 1 publication

(1 citation statement)

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“…Women with maternal complications of pregnancy and complications of the placenta, cord, and membranes had a higher risk of having stillbirth as compared to women with no identified complication. The finding was complementary to studies conducted in Ethiopia ( 74 ), Iran ( 75 ), India ( 76 ), and Pakistan ( 77 ). This might be explained by the deteriorated maternal condition resulting in vessel compression and cessation of blood flow, as well as fetal perfusion.…”

Section: Discussioncontrasting

confidence: 51%

Determinants of stillbirth among reviewed perinatal deaths in Ethiopia

et al. 2022

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BackgroundThe global burden of stillbirth has declined over time. However, the problem is still prominent in South Asian and Sub-Saharan African countries. Ethiopia is one of the top stillbirth-reporting countries worldwide. Despite several measures taken to reduce the burden of stillbirth; the pace of decline was not as good as the post-neonatal death. Thus, this study is aimed at identifying potential factors related to stillbirth in Ethiopia based on nationally reviewed perinatal deathsMethodThe national perinatal death surveillance data were used for this study. A total of 3,814 reviewed perinatal death were included in the study. Two model families,namely generalized estimating equation, and alternating logistic regression models from marginal model family were employed to investigate the risk factors of stillbirth. The alternating logistic regression model was selected as the best fit for the final analysis.ResultAmong reviewed perinatal deaths nearly forty percent (37.4%) were stillbirths. The findings from the multivariate analysis demonstrated that the place of birth (in transit and at home), cause of death (infection, and congenital and chromosomal abnormalities), maternal health condition (women with complications of pregnancy, placenta, and cord), delay one (delay in deciding to seek care) and delay three (delay in receiving adequate care) were associated with an increased risk of having a stillbirth. On the other hand, maternal education (women with primary and above education level) and the type of health facility (women who were treated in secondary and tertiary health care) were associated with a decreased risk of having a stillbirth.ConclusionThe study identified that both individual (place of delivery, cause of death, maternal health condition, maternal education, and delay one) and facility level (type of health facility and delay three) factors contributed to stillbirth outcome. Therefore, policies that are aimed at encouraging institutional delivery, improving health seeking behavior, and strengthening facility-level readiness should be devised to reduce the high burden of stillbirth in Ethiopia.

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