Incidence and mortality of primary sclerosing cholangitis in the UK: A population-based cohort study

Epidemiology of primary sclerosing cholangitis and primary biliary cirrhosis: A systematic review

“…Of included articles, 19 reported incidence or prevalence rates in Europe [16][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34], seven in North-America [35][36][37][38][39][40][41], three in Asia [42][43][44], and two in Australia [45,46]. Studies varied in size from 10 to 770 patients in catchment areas from 100,312 to 19,230,000 inhabitants.…”

“…Eight studies reported the proportion of concomitant IBD in PSC patients ranging from 20% in Singapore up to 76% in Sweden [27,[31][32][33][34]39,40,44]. When combining studies that met all quality criteria, the average proportion of IBD in PSC patients was 70% (67-73%) [27,39,40].…”

“…When combining studies that met all quality criteria, the average proportion of IBD in PSC patients was 70% (67-73%) [27,39,40]. Temporal trends in PSC incidence were reported in four studies, all of which demonstrated increasing incidence rates in time [31,34,40,32].…”

Primary Sclerosing Cholangitis in an Elderly Patient: A Diagnostic Challenge

“…Its epidemiological charcterisics lead to a higher disease prevalence in the fourth and fifth decades of life. A meta-analysis of data included from eight studies in Europe and North America reported that only one patient aged more than 84 years was diagnosed as having this disease 2,3) ; however, Japan is the only country that reported a second peak of incidence in the sixth decade of life. In its latest revision, the study found that 3 of 388 patients with PSC were older than 80 years 4) .…”

Primary Sclerosing Cholangitis

“…A more recent study from the UK where the incidence rates during the period between 1991 and 2001 were analysed showed the rate of the disease to be 0.41/100000 person-years and the prevalence in 2001 of 3.85/ 100000. Authors found that the incidence of PSC over the analyzed period increased by 50% (Card et al 2008).…”