Incidence and nature of infectious disease in patients treated with anti-TNF agents

Raychaudhuri, S. P.; Nguyen, Caroline T.; Raychaudhuri, Smriti K.; Gershwin, M. Eric

doi:10.1016/j.autrev.2009.08.006

Cited by 60 publications

(51 citation statements)

References 264 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The Journal of Immunology, 2010, 185: 4292-4301. P harmacological neutralization of TNF is a highly effective therapy, in particular in rheumatoid arthritis, but increased incidence of granulomatous infections, such as tuberculosis, has been associated with TNF blockade (1). The two classes of TNF antagonists, based on either soluble TNFR (etanercept) or mAbs against human TNF (such as infliximab or adalimumab), differ with respect to kinetics and mechanisms of action (2)(3)(4).…”

mentioning

confidence: 99%

Limited Role for Lymphotoxin α in the Host Immune Response toMycobacteriumtuberculosis

Allie

Keeton

Court

et al. 2010

The Journal of Immunology

View full text Add to dashboard Cite

mentioning

confidence: 99%

Limited Role for Lymphotoxin α in the Host Immune Response toMycobacteriumtuberculosis

Allie

Keeton

Court

et al. 2010

The Journal of Immunology

View full text Add to dashboard Cite

“…Treatment may cause reactivation of latent infection with M. tuberculosis, M. bovis, T. gondii, and Brucella spp. (Wallis et al, 2004;Young and McGwire, 2005;Lassoued et al, 2007;Raychaudhuri et al, 2009). Tuberculosis occurred in two patients (one with RA and one with Crohn's disease) treated with infliximab, because of reactivation of M. bovis (Larsen et al, 2008;Nager et al, 2009).…”

Section: Immunosuppressant Therapies That Increase the Risk Of Foodbomentioning

confidence: 99%

“…Cryptosporidium and T. gondii (Klein et al, 2001). Listeriosis is often associated with older age and concomitant use of immunosuppressants such as methotrexate (MTX), a corticosteroid and a biological agent (Slifman et al, 2003;Raychaudhuri et al, 2009). Listeria endocarditis occurred in a psoriatic arthritis patient treated with the biological agent infliximab who admitted eating soft cheeses (Kelesidis et al, 2010).…”

Section: People With Pathological or Iatrogenic Immunosuppressionmentioning

confidence: 99%

See 1 more Smart Citation

The Occurrence and Prevention of Foodborne Disease in Vulnerable People

Lund

O’Brien

2011

Foodborne Pathogens and Disease

175

110

View full text Add to dashboard Cite

In developed countries, such as the United Kingdom and the United States, between 15% and 20% of the population show greater susceptibility than the general population to foodborne disease. This proportion includes people with primary immunodeficiency, patients treated with radiation or with immunosuppressive drugs for cancer and diseases of the immune system, those with acquired immune-deficiency syndrome and diabetics, people suffering from liver or kidney disease or with excessive iron in the blood, pregnant women, infants, and the elderly. Malnutrition and use of antacids, particularly proton-pump inhibitors, also increase susceptibility. We review the occurrence of infection by foodborne pathogens in these groups of people and measures to prevent infection. The nature and use of low microbial diets to reduce the risk of foodborne disease in immunocompromised patients are very variable. Diets for vulnerable people in care should exclude higherrisk foods, and vulnerable people in the community should receive clear advice about food safety, in particular avoidance of higher-risk foods and substitution of safer, nutritious foods.

show abstract

“…Biologic products are usually safe and tolerable. But, like all medications, they have side effects and can prone the patients to infections and increased their risk of developing a malignancy [13][14][15][16].…”

Section: Introductionmentioning

confidence: 99%

Healing Effect of Moringa oleifera Lam against UV-B Induced Psoriasis form Changes in Rats

Dilawar¹,

Shah²,

Hussain³

et al. 2017

Biochem Pharmacol (Los Angel)

View full text Add to dashboard Cite

Moringa oleifera extracts have been used in herbal medicines by various communities in different parts of the world. It is a multipurpose tree with a magnificent profile of medicinal uses, high nutritional values and pharmacological activities. Various parts of this plant such as the flower, seed, immature pod, stem bark, leaf and root, possesses anti-oxidant, anticancer, antimicrobial, anti-ulcer, anti-hepatotoxic, antihypertensive, antihyperlipidemia, antidiabetic, antispasmodic, antiepileptic, antipyretic, anti-inflammatory and analgesic properties. An attempt was made to evaluate the healing properties of the methanolic extract of different aerial parts of Ultraviolet light-B was used to induce psoriasisform changes in rats. Irradiated rats were divided into 8 groups (6 rats/groups). The first group left untreated served as a control were given normal lab feed and a second group which served as the standard was administered retinoic acid (0.5 mg/kg) orally. Group III to Group VIII were administered orally with the methanolic extracts from aerial parts of M. oleifera (200 mg/kg bw) and (400 mg/kg bw). Data collected in this study was analyzed using statistical package for social sciences (SPSS) version 16. There was a significant difference (P<0.05) in epidermal thickness of control and drugs treated group. The methanolic extracts from aerial parts of M. oleifera used for treatment, enhanced fibroplasia, reduced inflammation and produced high amounts of scar tissue and enhanced the rate of wound healing and re-epithelisation compared to control. The plant extracts were effective against psoriasiform changes in rats. Though, more studies are required to assess which of its known ingredients are responsible for the antipsoriatic effects. The constituents of M. oleifera should be considered for further studies.

show abstract

Incidence and nature of infectious disease in patients treated with anti-TNF agents

Cited by 60 publications

References 264 publications

Limited Role for Lymphotoxin α in the Host Immune Response toMycobacteriumtuberculosis

Limited Role for Lymphotoxin α in the Host Immune Response toMycobacteriumtuberculosis

The Occurrence and Prevention of Foodborne Disease in Vulnerable People

Healing Effect of Moringa oleifera Lam against UV-B Induced Psoriasis form Changes in Rats

Contact Info

Product

Resources

About