While central venous catheterization (CVC) is used extensively and for a spectrum of medical indications, including dialysis access, the procedure is not without risks. Addressing and acknowledging potential complications is informative, as such insight can improve patient outcomes and establish clinical guidelines. We present the case of a 34-year-old male with dermatomyositis who sustained a subclavian artery injury in the intensive care unit following internal jugular vein catheterization. This case raises awareness of this complication to enable us to promptly identify and manage similar patients in the future, as well as emphasize refining the procedural technique of physicians at all levels. Due to the rarity of CVC vessel injury, literature describing the consequences is scarce. We discuss teamwork and safety culture, emphasizing how interventions can reduce error risk by improving team collaboration, leader responsiveness, and above all patient outcomes.