Incidence and Outcomes of Contrast-Induced Nephropathy After Computed Tomography in Patients With CKD: A Quality Improvement Report

Contrast Material–induced Nephrotoxicity and Intravenous Low-Osmolality Iodinated Contrast Material: Risk Stratification by Using Estimated Glomerular Filtration Rate

“…There are several recent studies that addressed CIN risk stratification on the basis of pre-CT eGFR (26)(27)(28). Kim et al (26) studied 520 patients who were imaged with contrast-enhanced CT and reported the incidence of CIN for three eGFR ranges (45-59, 30-44, ,30 mL/ min/1.73 m 2 ); the incidence of CIN was 0.0%, 2.9%, and 12.1%, respectively.…”

“…If CIN risk stratification is clinically converted from the more commonly and determined that incidence of CIN was dependent on the eGFR range analyzed: 0.6% for eGFR of 41-59 mL/ min/1.73 m 2 ; 4.6% for eGFR less than 40 mL/min/1.73 m 2 ; and 7.8% for eGFR less than 30 mL/min/1.73 m 2 . However, in all three studies (26)(27)(28), the authors did not include a control group of patients who were not exposed to contrast material, and all post-CT AKI events were assumed to be CIN. Therefore, it was difficult to interpret these data.…”

Comparison of Aortic Annulus Dimension After Aortic Valve Neocuspidization With Valve Replacement and Normal Valve

“…Several previous studies have identified a baseline eGFR <45 mL/ min per 1.73 m 2 to be associated with an increased risk of contrast-induced nephropathy. 10,11 We therefore excluded patients with an eGFR below baseline. No significant AR was observed with postoperative ultrasound cardiography (UCG) in the AVNeo group.…”

Guidelines on the use of iodinated contrast media in patients with kidney disease 2012: digest version

“…Weisbord et al [5] reported that the risk of CIN among outpatients after computed tomography (CT) with intravenous iodinated contrast media increased significantly among those with an eGFR of \45 mL/min/1.73 m 2 , and Kim et al [6] reported that the incidence of CIN after contrast-enhanced CT was 0 % among patients with a baseline eGFR of 45-59 mL/min/1.73 m 2 , 2.9 % among those with 30-44 mL/min/1.73 m 2 , and 12.1 % among those with \30 mL/min/1.73 m 2 .…”

“…Because the risk for developing CIN after intravenous administration of contrast media is considered high in patients with an eGFR of \45 mL/min/ 1.73 m 2 (see CQ3-1) [5,6], such patients should have the risk of CIN explained to them, and receive appropriate measures to prevent CIN such as fluid therapy before and after contrast-enhanced CT (see CQ7-1).…”