Incidence and Phenotypic Characteristics of Pediatric IBD in Northeastern Slovenia, 2002–2010

Abstract

The incidence of childhood IBD in the northeastern part of the country is high and comparable with that reported from the developed western countries of Europe, and is probably still increasing. This increase may be the result of changes in the lifestyle, especially in dietary habits during the last 20 years.

One-year prospective registry of inflammatory bowel disease in the Argentine pediatric population

“…[7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26] The incidence in the Autonomous City of Buenos Aires was 2.4/100 000, closest to other reports, whereas a very low incidence was reported in the province of Buenos Aires, even lower than in other provinces. In Greater Buenos Aires, which comprises 24 districts, the same number of patients was registered in the same period as in the Autonomous City of Buenos Aires; however, the rate was low (0.4/100 000) due to the population size.…”

“…Since there are no other data on incidence available in Argentina and Latin America, and considering clinical differences in our patients compared to those of the bibliography, 26,27 we propose the creation of an ongoing registry at a national level to reinforce these findings.…”

Long-term outcome of immunomodulator use in pediatric patients with inflammatory bowel disease

“…In the past two decades, the therapeutic approaches in children have shifted to more early intervention with immunomodulators in an attempt to achieve tight control of inflammation with endoscopic healing and/or normalization of biomarkers [1,[33][34][35][36][37]. Despite adopting this approach in our center for many years now, we here show that only 32% of pediatric IBD patients treated with conventional therapy remained free of biologics or surgery 5-years after diagnosis and more than two thirds of patients required stepup treatment.…”

Registro prospectivo durante un año de enfermedad inflamatoria intestinal en población pediátrica argentina

“…[7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26] La incidencia en la CABA alcanzó 2,4/100 000, más cercana a las reportadas, mientras la provincia de Buenos Aires reportó una incidencia muy baja, incluso, respecto a otras provincias del país. En el Gran Buenos Aires, que comprendió 24 partidos del conurbano, se registraron, durante el mismo período, igual número de pacientes que en la CABA, pero la tasa obtenida fue baja (0,4/100 000), debido al elevado número poblacional.…”

“…Dado que no se cuenta con otros datos de incidencia en nuestro país y en Latinoamérica y considerando las diferencias clínicas de nuestros pacientes respecto de la bibliografía disponible, 26,27 se propone la creación de un registro permanente de todo el país con el objeto de consolidar estas observaciones.…”