Incidence and Prediction of Ischæmic Heart-Disease in London Busmen

Morris, J.N.; Kagan, A; Pattison, Denise; Gardner, Michael; Raffle, P. A. B.

doi:10.1016/s0140-6736(66)93034-0

Cited by 368 publications

(84 citation statements)

References 19 publications

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“…The crosssectional study demonstrated a higher prevalence of questionnaire-positive angina pectoris among bus drivers than among locomotive engineers (27). Studies from London and Norway have reported similar results (16,26). The bus drivers in the Danish studies demonstrated a marked maladaptation to work, experienced poor work environment, and evinced pronounced mental symptoms.…”

supporting

confidence: 55%

“…Serum cholesterol was found to be higher in bus drivers than in other men, and it normalized after retirement from work (28). Similar results were found in England and Norway (13,26). As some of the mechanisms leading to the elevated relative risk among urban bus drivers could have been affected by serum cholesterol and blood pressure due to stress (8, II), a confounder control with regard to these risk factors would lead to overmatching and reduce the effect of the objective work load (38).…”

Section: Discussionmentioning

confidence: 52%

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Impact of work-related and psychosocial factors on the development of ischemic heart disease among urban bus drivers in Denmark.

Netterstrøm

Juel²

1988

Scand J Work Environ Health

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NETTERSTR0M B, JUEL K. Impact of work-related and psychosocial factors on the developmentof ischemic heart disease among urban bus drivers in Denmark. Scand J Work En viron Health 14 (1988) 231-238. From 1978 to 1985, 2 465 male bus drivers in the three major cities in Denmark were followed with regardto hospitaladmissiondue to myocardial infarction(Ml) and death due to ischemic heart disease (lHD). In all 2 045 (83 010) of these men responded in 1978 to a questionnaire on psychosocial well-being and work conditions. The respondents did not differ from the nonrespondents regardinghospital admissions and death in the follow-up period (1978)(1979)(1980)(1981)(1982)(1983)(1984). Sixty-two cases of MI were registered among the 2045 bus driversin 1978-1984. On this basis relativerisk for MI was calculated with a multiple regression model for independent variablesregarding psychosocial well-being and work conditions. High work load (drivingin heavytraffic) wassignificantly associatedwith the occurrenceof MI. Of the psychosocial factors "no socialcontact with colleagues" and "increased work pace" werealso significantly associated with the occurrence of MI. Smokinghabits tended to be associated with the occurrence of MI, whilestress symptoms and job dissatisfaction did not. The mental burden on bus drivers working in heavy traffic seems a possible explanation for the findings.

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supporting

confidence: 55%

Section: Discussionmentioning

confidence: 52%

Impact of work-related and psychosocial factors on the development of ischemic heart disease among urban bus drivers in Denmark.

Netterstrøm

Juel²

1988

Scand J Work Environ Health

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“…Morris and coworkers published a landmark study in which they reported differences in CHD rates experienced by London bus drivers, who had high CHD rates, and ticket takers, who had low CHD rates (22). The drivers sat all day whereas the ticket takers climbed up and down the double-decker buses collecting fares, suggesting an association between physical activity and CHD rates.…”

Section: Review Of the Literaturementioning

confidence: 99%

Major public health benefits of physical activity

Macera¹,

Hootman²,

Sniezek³

2003

Arthritis & Rheumatism

148

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“…An investigation of London busmen soon after also concluded that systolic pressure was a better predictor of hypertensive events following coronary disease. 10 In 1969 the Framingham Study disputed the accepted notion that the adverse consequences of hypertension derive chiefly from the diastolic pressure for coronary disease and a year later for stroke. 11,12 Several years later these findings of an equal or greater influence of systolic pressure were extended to peripheral artery disease and heart failure.…”

Section: Components Of Blood Pressurementioning

confidence: 99%

Fifty years of Framingham Study contributions to understanding hypertension

2000

J Hum Hypertens

237

120

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The Framingham Study established hypertension as a major cardiovascular risk factor and quantified its atherogenic cardiovascular disease potential. An historical perspective is presented on the epidemiological insights about hypertension derived from 50 years of Framingham Study research into the prevalence, incidence, determinants and hazards of hypertension. Existing misconceptions about the presence of critical levels of blood pressure, the impact of the systolic and diastolic components of blood pressure, the hazard 'mild' hypertension, the impact in advanced age and the hazard of left ventricular hypertrophy. The importance of isolated systolic hypertension and the pulse pressure were demonstrated. It has been demonstrated that hypertension seldom occurs in isolation of other athero-

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Incidence and Prediction of Ischæmic Heart-Disease in London Busmen

Cited by 368 publications

References 19 publications

Impact of work-related and psychosocial factors on the development of ischemic heart disease among urban bus drivers in Denmark.

Impact of work-related and psychosocial factors on the development of ischemic heart disease among urban bus drivers in Denmark.

Major public health benefits of physical activity

Fifty years of Framingham Study contributions to understanding hypertension

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