Incidence and predictors of diabetic ketoacidosis among children with diabetes in west and east gojjam zone referral hospitals north west Ethiopia, 2019.

Assefa, Birtukan; Zeleke, Haymanot; Murugan, Rajalakshmi; Wondwossen, Kalkidan

doi:10.21203/rs.3.rs-50229/v1

Cited by 1 publication

(1 citation statement)

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“…The proportion of children diagnosed with DKA in Addis Ababa, Ethiopia, was high (35.8%) [10]. Likewise, in Gojjam, Ethiopia, the overall incidence rate of DKA was 2.27 per 100 children/month of observation [16].…”

Section: Introductionmentioning

confidence: 95%

Treatment Outcome and Associated Factors among Type 1 Diabetic Children Admitted with DKA in Bahir Dar City Public Referral Hospital, Northwest, Ethiopia: A Cross-Sectional Study

Fentahun,

Silenat,

Tilaye

et al. 2023

Int Arch Endocrinol Clin Res

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Background: Length of hospital stay, complication and mortality are the primary outcomes that should be measured during diabetic ketoacidosis management. However, data associated with the length of stay, complications, and mortality rate due to diabetic ketoacidosis remains limited in Ethiopia. In addition, nonfiction is very scarce about factors associated with treatment outcomes starting from its initial presentation and the overall management process. Therefore, this study was aimed to assess the treatment outcomes of children admitted with diabetic ketoacidosis at the Felege Hiwot comprehensive referral hospital, North West, Ethiopia. Methods:A cross-sectional study was conducted among children admitted with diabetic keto acidosis between 2016 and 2021. Data were collected using the data abstruction tool. Then, stored in Epi-dataversion 4.6 and exported into STATA 14.0 statistical software for analysis. Catagorical variables were described using proportions and compared using the Chi-squre test; Whereas, continuous parametric variables with median and standard deviations were compared using parametric(t-test). Model goodness of fit and assumptions were checked. The association between independent variables and length of hospital stay was assessed using binary logistic regression. Finally, variables with p-value < 0.05 were considered as statistically significant. Result:The median length of hospital stay was 8 ± 6.2 days. 59.3% of the patients had along hospital stay (> 7 days). The majority of patients (97.5%) improved and were discharged with 14.2% complications and 4(2.5%) died in the hospital. Factors that affected longer hospital stay were Residence (aOR = 4.31; 95CI = 1.25-14.80), family history of diabetes (aOR = 0.12; 95% CI = 0.02-0.64), glycemia at addmision (aOR =1.01; 95% CI = 1.00-1.02), insulin skipping (aOR = 0.08; 95% CI = 0.01-0.98), abdominal pain (aOR = 4.28; 95% CI = 1.11-15.52) and time in which the patient get out of diabetic ketoacidosis (aOR = 6.39; 95% CI = 1.09-37.50). Conclusion:Majority of patients showed improvement and were discharged to their homes after a long hospital stay and with a very low mortality rate followed by complications (14.2%). The time in which the majority of patients got out of diabetic ketoacidosis were between 24-48 hours. Thus, to achieve intended treatment outcome early in time, clinicians and other stakeholders should focus on diabetic ketoacidosis presentation and precipitating factors with possible multicenter studies.

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Section: Introductionmentioning

confidence: 95%