Incidence and prevalence of inflammatory bowel diseases in gastroenterology primary care setting

Tursi, Antonio; Elisei, Walter; Picchio, Marcello

doi:10.1016/j.ejim.2013.06.005

Cited by 24 publications

(14 citation statements)

References 22 publications

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“…When examining the epidemiology in patients with SCAD through the primary care setting, the incidence was 4/100,000, the median age was 68, and the mean time between onset of symptoms to diagnosis was 36 months. 11 The prevalence of SCAD in patients with diverticulosis was seen to be over 11% in prospective endoscopic studies. 12 As previously mentioned, SCAD primarily occurs in the elderly, and it coincides with the second peak of incidence of IBD in the elderly.…”

Section: Epidemiologymentioning

confidence: 99%

Considerations and Changes in the Evaluation, Management, and Outcomes in the Management of Diverticular Disease: The Diagnosis, Pathology, and Treatment of Diverticular Colitis

Kucejko

Poggio

2018

Clinics in Colon and Rectal Surgery

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Diverticular colitis, also known as segmental colitis associated with diverticulosis, is a colonic inflammatory disorder on the spectrum of inflammatory bowel disease (IBD). The disease consists of macroscopic and microscopic inflammation affecting inter-diverticular mucosa, sparing peri-diverticular mucosa, with inflammation confined to the descending and sigmoid colon. The disease likely arises from the altered immune response of an individual, genetically susceptible to the IBD spectrum of diseases. Patients with segmental colitis associated with diverticulosis (SCAD) are typically older, and likely represent a subgroup of IBD-susceptible patients who lacked an environmental trigger until that point in their life. Most patients remain in remission with initial treatments of mesalamine or topical steroids, and maintenance mesalamine afterwards. Only the most severe form of the disease necessitates immunomodulatory therapy and the consideration of surgery.

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Section: Epidemiologymentioning

confidence: 99%

Considerations and Changes in the Evaluation, Management, and Outcomes in the Management of Diverticular Disease: The Diagnosis, Pathology, and Treatment of Diverticular Colitis

Kucejko

Poggio

2018

Clinics in Colon and Rectal Surgery

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“…12 IBD-like inflammation may occur in patients with diverticulosis and its prevalence is increasing in clinical setting. 13 Ulcerative colitis rarely occurs in diverticulosis. In a recent prospective study, the prevalence of UC was < 1%, 14 which is significantly lower than SCAD prevalence in a clinical setting.…”

Section: Diverticular Disease and Chronic Idiopathic Inflammatory Bowmentioning

confidence: 99%

Management of Diverticular Disease in the Setting of Other Colorectal Pathology: Data on Simultaneous Issues in Segmental Colitis, Inflammatory Bowel Disease, Cancer, and Complications

Ghalyaie

2018

Clinics in Colon and Rectal Surgery

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Diverticulosis of the colon is a very common anatomical condition. In the Western world, it affects more than 70% of over 65 years old population and represents the fifth most important gastrointestinal disease in terms of health care costs in Western countries. The diagnosis of diverticular disease and diverticulitis can be challenging. Often, there is overlap with other colonic pathologies, such as segmental colitis, ischemia, inflammatory bowel disease, cancer, or infectious colitis. Management of diverticular disease in these settings might be different.

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“…Hence, the number of applications may yield an estimate of the prevalence of IBD in Italy. Such estimates, dating back to 2009[1], are showing an IBD prevalence in Italy of 177-254 cases/10 5 . Regional incidence data of pooled Crohn’s disease (CD) and ulcerative colitis (UC) yield figures between 2.7 and 13 cases per 10 5 per year.…”

Section: Epidemiologymentioning

confidence: 99%

Inflammatory bowel disease: Efficient remission maintenance is crucial for cost containment

Actis

Pellicano

2017

WJGPT

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The inflammatory bowel diseases (IBD) are chronic incurable inflammatory disorders of the gut. Some 10% run a downhill course, requiring emergency medical support and often surgery; another small subset are monogenic, and, threatening pediatric patients, are the challenge of these days. The majority of the IBDs, however, are polygenic low-penetrance diseases, running a lifetime waxing-and-waning course. The prevalent trend is towards a slow worsening and steady cost increase. Each and all drugs of the available arsenal exhibit strengths and weaknesses: Mesalamines are chiefly effectively for mild-moderate colitis, and do not work in Crohn’s; steroids do not control some 40% of the ulcerative colitis cases, and are not indicated for Crohn’s; thiopurines are effective in the maintenance of the IBDs but do not prevent relapses on withdrawal; biologics are still being used empirically (not monitored) causing further increase of their cost over that of hospitalization. Against all these caveats, two simple rules still hold true: Strict adherence maintenance and avoidance of colitogenic drugs. This matter is expanded in this minireview.

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Incidence and prevalence of inflammatory bowel diseases in gastroenterology primary care setting

Cited by 24 publications

References 22 publications

Considerations and Changes in the Evaluation, Management, and Outcomes in the Management of Diverticular Disease: The Diagnosis, Pathology, and Treatment of Diverticular Colitis

Considerations and Changes in the Evaluation, Management, and Outcomes in the Management of Diverticular Disease: The Diagnosis, Pathology, and Treatment of Diverticular Colitis

Management of Diverticular Disease in the Setting of Other Colorectal Pathology: Data on Simultaneous Issues in Segmental Colitis, Inflammatory Bowel Disease, Cancer, and Complications

Inflammatory bowel disease: Efficient remission maintenance is crucial for cost containment

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