Incidence and Prevalence of Myasthenia Gravis in Korea: A Population-Based Study Using the National Health Insurance Claims Database

Park, Suyeon; Lee, Jin Yong; Lim, Nam Gu; Hong, Yoon Ho

doi:10.3988/jcn.2016.12.3.340

Cited by 46 publications

(35 citation statements)

References 23 publications

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“…The other 3% are supported by a Medical Aid Service (MAS) which is run by the government for low income individuals. As of 2011, there were 50,908,646 of the total Korean population, composing of 49,299,165 (96.8%) NHI beneficiaries and 1,609,481 (3.2%) MAS recipients [12]. The Health Insurance Review and Assessment Service (HIRA) is an independent Korean government agency responsible for evaluating medical claim data from all healthcare organizations and medical facilities.…”

Section: Methodsmentioning

confidence: 99%

Incidence of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Nationwide Population-Based Study Using National Health Insurance Database in Korea

et al. 2016

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BackgroundStevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening diseases; however, it is hard to estimate their incidence due to the rarity of these diseases. We evaluated the incidence of SJS and TEN using a nationwide administrative database.MethodsWe used a national medical insurance review system (Health Insurance Review and Assessment) database which contained the claim data of the entire nation from 2009 to 2013 to estimate the accurate incidence of SJS and TEN in Korea. The diagnostic codes of L511 (SJS) or L512 (TEN) from the International Classification of Diseases-10th revision were used to define the target study population. We also retrospectively followed up a 2011 SJS and TEN cohort for 24 months in order to assess the in-hospital mortality, related complications and total claims cost due to SJS and TEN.ResultsA total of 1,167 (938 SJS and 229 TEN) cases were newly diagnosed from 2010 to 2013. The age- and sex-standardized annual incidences estimated in this study were 3.96 to 5.03 in SJS and 0.94 to 1.45 in TEN per million. There was no significant change in annual incidence throughout the study periods. When analyzed by 10-year age groups, the annual incidence was the lowest in group 20–29 years and the highest in group 70 for both SJS and TEN. Based on the 2011 cohort analysis, the in-hospital mortality were 5.7 and 15.1% for SJS and TEN, respectively. The mortality increased with age, particularly, after 40 years of age. Among the complications related with SJS or TEN, ocular sequelae was the most common (43.1 and 43.4% of SJS and TEN patients, respectively) followed by urethral sequelae (5.7 and 9.4% of SJS and TEN patients, respectively).ConclusionOverall, our data suggest that SJS, and TEN are infrequent but constantly arise throughout the years.

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Section: Methodsmentioning

confidence: 99%

Incidence of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Nationwide Population-Based Study Using National Health Insurance Database in Korea

et al. 2016

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“…The law requires that all citizens have an insurance plan under the National Health Insurance Service (NHIS). As a single insurer, NHIS oversees the collection of data on all medical service utilization during the reimbursement process . Therefore, NHIS claims data is representative of the entire Korean population.…”

Section: Introductionmentioning

confidence: 99%

Burden of dental caries and periodontal disease in South Korea: An analysis using the national health insurance claims database

Radnaabaatar

Kim

et al. 2019

Comm Dent Oral Epid

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Objectives: It is essential to measure and monitor the burden of dental caries and periodontal disease (PD) in Korea's ageing population due to their potential impact on morbidity, quality of life and economic condition. This study aimed to quantify the size of burden of dental caries and PD using the disability-adjusted life years (DALYs), and their trends.Methods: DALYs were estimated using incidence-based approaches to calculate the burden of dental caries and PD from 2013 to 2015 in Korea. Incidence and prevalence were estimated using medical claim data by specific algorithms. Additionally, sensitivity analysis was conducted to investigate possible weakness in the study methodology. To conduct the sensitivity analysis, we modified the algorithms to estimate prevalence and incidence.

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“…1,2,4,9 Korea has a National Health Insurance (NHI) system. 9,10 This universal health-care system has enrolled all residents and includes all medical institution types in South Korea. 9,10 The NHI claims database includes extensive patient information and all medical records.…”

Section: Introductionmentioning

confidence: 99%

“…9,10 This universal health-care system has enrolled all residents and includes all medical institution types in South Korea. 9,10 The NHI claims database includes extensive patient information and all medical records. In the current study, we performed a nationwide cross-sectional study focused on comorbid rheumatic disorders in vitiligo patients using the NHI claims database.…”

Section: Introductionmentioning

confidence: 99%

Increased risk of comorbid rheumatic disorders in vitiligo patients: A nationwide population‐based study

Choi

Eun

Choi

et al. 2017

The Journal of Dermatology

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Vitiligo is a common acquired depigmentation disorder. Previous studies have shown that vitiligo is associated with a variety of autoimmune disorders. However, a large-scale epidemiological study focused on comorbid rheumatic disorders has not been undertaken. To clarify the associations between vitiligo and various rheumatic disorders, we performed a cross-sectional study using data from the Korean National Health Insurance claims database. Between 2009 and 2013, totals of 86 210 patients with vitiligo and 172 420 age- and sex-matched controls without vitiligo were enrolled in this study. Vitiligo patients were found to be at increased risk of systemic lupus erythematosus, systemic sclerosis, Sjögren's syndrome and rheumatoid arthritis, but no significant association was found between vitiligo and dermatomyositis/polymyositis, Behçet's disease or ankylosing spondylitis. Subgroup analysis showed an increased risk of dermatomyositis/polymyositis in male and ankylosing spondylitis in female vitiligo patients. The risks of dermatomyositis/polymyositis or ankylosing spondylitis were higher in young vitiligo patients. Our study confirms a significant association between vitiligo and rheumatic disorders. Differences in comorbid rheumatic disorders by age group and sex suggest the need for patient-specific approaches. Careful consideration of rheumatic disorders is required for the proper management of comorbidities in vitiligo patients.

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Incidence and Prevalence of Myasthenia Gravis in Korea: A Population-Based Study Using the National Health Insurance Claims Database

Cited by 46 publications

References 23 publications

Incidence of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Nationwide Population-Based Study Using National Health Insurance Database in Korea

Incidence of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Nationwide Population-Based Study Using National Health Insurance Database in Korea

Burden of dental caries and periodontal disease in South Korea: An analysis using the national health insurance claims database

Increased risk of comorbid rheumatic disorders in vitiligo patients: A nationwide population‐based study

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