“…Regarding the risk of CRC in paediatric UC population, although studies are scarce, they have also reported higher incidence rates than the overall rate for adults with UC, 62, 63, 70 thus supporting previous findings, 13,14 namely, that early onset of UC 7, 8 could confer a higher risk of developing CRC. 28,29,83 Considering only population-based studiesthat is, excluding studies from referral centresthe incidence rate of CRC is even lower.…”