Incidence and profile of benign epithelial tumors of salivary glands from a single center in Northeast of Brazil

Abstract

Background Benign tumors of the salivary glands are a group of lesions with varied histopathological and clinical spectrum. The aim was to determine the incidence and clinicopathological characteristics of benign salivary gland neoplasms diagnosed between 2007 and 2016 in a single center located in northeastern Brazil. Material and Methods Records regarding sex, age, anatomical location, histopathological subtype and treatment were retrieved, and data were analyzed using the Stata/IC software (version 12.0). Results There were above 7,100 cases of neoplasms in the head and neck region, of which 403 corresponded to salivary gland neoplasms. Of these, 238 (59%) were benign, being pleomorphic adenoma (PA) the most frequent neoplasm (n=178; 74.8%), followed by Warthin's tumor (WT) (n=23; 9.7%). Overall, most cases occurred in females (n=136; 57.1%) and age ranged from 11 to 83 years. The parotid gland (n=188; 79%) was the most common anatomical site, and all patients were treated by surgical excision. Of the cases diagnosed as PA, malignant transformation to carcinoma ex-pleomorphic adenoma (CAEXPA) occurred in 7 (3.9%) cases. Conclusions The present study confirmed the clinical and demographic profile of benign salivary gland neoplasms, which contributes to the continuous knowledge of current data about these lesions. Key words: Salivary gland, benign neoplasms, epidemiology.

Surgical interventions for management of benign parotid tumors: Systematic review and network meta‐analysis

“…Among all types of parotid gland tumors, benign tumors are the most common, with an incidence rate of 75%–80% 2,3 . Pleomorphic adenoma is the most frequent benign parotid tumor, representing 35% of all parotid neoplasms and 60%–70% of all benign tumors, followed by adenolymphoma (Warthin tumor) 3,4 …”

“…2,3 Pleomorphic adenoma is the most frequent benign parotid tumor, representing 35% of all parotid neoplasms and 60%-70% of all benign tumors, followed by adenolymphoma (Warthin tumor). 3,4 Surgical excision has long been considered the most effective treatment regimen for parotid tumors, but the choice of which technique to be used remains a topic of controversy. 5 Based on the extent of resection, parotid surgery can be roughly classified into enucleation, extracapsular dissection (ECD), partial superficial parotidectomy (PSP), superficial parotidectomy (SP), and total parotidectomy (TP).…”

Malignant salivary gland tumors: agreement between fine needle aspiration biopsy, incisional biopsy and final histopathological diagnostic

“…The salivary glands comprise four pairs of major glands: parotid, submandibular, sublingual and, recently described, tubarial - located in the nasopharynx ( 1 ), in addition to the minor salivary glands that are numerous and widely distributed in the mouth and oropharynx ( 2 ). The neoplasms of the salivary glands are uncommon, constituting about 3% to 6% of all tumors of the head and neck and are characterized by a great heterogeneity of histological characteristics, biological behaviors and clinical outcomes ( 3 - 5 ).…”