Incidence and Prognostic Value of Early Repolarization Pattern in the 12-Lead Electrocardiogram

Haruta, Daisuke; Matsuo, Kiyotaka; Tsuneto, Akira; Ichimaru, Shinichiro; Hida, Ayumi; Sera, Nobuko; Imaizumi, Misa; Nakashima, Eiji; Maemura, Koji; Akahoshi, Masazumi

doi:10.1161/circulationaha.110.006460

Cited by 218 publications

(155 citation statements)

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“…Another study conducted by Haisaguerre et all showed the prevalence of 1-13 % and this may result from the intermittent occurrence of ER pattern (3,11). Our results were similar with Haruto`s study.…”

Section: Discussionsupporting

confidence: 91%

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Prevalance of early repolarization pattern in young healthy men

Yıldırım¹,

Avcı²,

Yıldırım³

et al. 2016

Med Sci and Discov

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Section: Discussionsupporting

confidence: 91%

“…Hypothermia, cocaine usage, Brugada syndrome and hypertrophic cardiomyopathy should be considered on differential diagnosis. Prevalence of ERP is 1-13 % in normal population and 15-70 % in patients with idiopathic VF (10,11). The rate is 44 % in young athletes and most of them have ascending ST segment pattern after J point (12).…”

Section: Introductionmentioning

confidence: 99%

Prevalance of early repolarization pattern in young healthy men

Yıldırım¹,

Avcı²,

Yıldırım³

et al. 2016

Med Sci and Discov

View full text Add to dashboard Cite

“…This suggests a particular young and male background that relates to heredity, hormonal factors, or autonomic nervous function. Haruta et al proposed a hypothesis that testosterone may modulate cardiac mortality in ERS 26. The plasma concentration of testosterone is higher in men with BrS than in other age‐matched men15 and was reported to increase net outward current of the epicardium, to aggravate the transmural voltage gradient between the epicardium and endocardium, and to lead to the J point seen in ERS and BrS 27.…”

Section: Discussionmentioning

confidence: 99%

Long‐Term Prognosis of Brugada‐Type ECG and ECG With Atypical ST‐Segment Elevation in the Right Precordial Leads Over 20 Years: Results From the Circulatory Risk in Communities Study (CIRCS)

Tsuneoka

Takagi

Murakoshi

et al. 2016

JAHA

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BackgroundBrugada syndrome is recognized as being associated with sudden cardiac death; however, the prevalence of non–type 1 Brugada‐type ECG (BrS) or atypical ST‐segment elevation in the right precordial leads (STERP) and the long‐term prognosis for those patients remain unknown.Methods and ResultsWe analyzed standard 12‐lead ECGs of 7178 apparently healthy participants (age range 40–64 years) who underwent health checkups from 1982 to 1986 in the Circulatory Risk in Communities Study, a prospective, large, community‐based cohort study in Japan. ECGs with J point amplitude ≥0.2 mV in the right precordial leads were divided into 3 groups: (1) type 1 BrS, (2) type 2 or 3 BrS (non‐type 1 BrS), and (3) STERP. The others served as the non–ST‐segment elevation group. We identified 8 participants (0.1%) with type1 BrS, 84 (1.2%) with non–type 1 BrS, and 228 (3.2%) with STERP. During a median follow‐up of 18.7 years (133 987.0 person‐years), sudden cardiac death was observed in no participants (0.0%) with type 1 BrS, in 1 (1.2%) with non–type 1 BrS, in 7 (3.1%) with STERP, and in 50 (0.7%) with non–ST‐segment elevation. Participants with STERP had a markedly elevated risk of sudden cardiac death (multivariable hazard ratio 3.9, 95% CI 1.7–9.0).Conclusions STERP was associated with an elevated risk of sudden cardiac death in a middle‐aged population.

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“…We classified ST-segment morphology after the J-point as horizontal or ascending (13,14). All ECGs were analyzed by 2 independent cardiologists (T.T., K.H.)…”

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confidence: 99%