Incidence and progression of ankle osteoarthritis: The johnston county osteoarthritis project

Jaleel, Ayesha; Golightly, Yvonne M.; Álvarez, Carolina; Renner, Jordan B.; Nelson, Amanda

doi:10.1016/j.semarthrit.2020.10.015

Cited by 21 publications

(19 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The difference in sex ratio between our two study groups may also have affected our results. In addition, a high BMI is regarded as a risk factor for ankle OA, as it is for OA of other joints 28) , and it has been reported that the higher BMI, the greater the probability that ankle OA will develop after 3 to 4 years 29) . The BMI of our patients with advanced ankle OA was significantly higher than that of our healthy subjects.…”

Section: Discussionmentioning

confidence: 99%

T1ρ Mapping of Subtalar Articular Cartilage in Patients with Ankle Osteoarthritis

Maki

Haraguchi

Asano

et al. 2021

J St. Marianna Univ

View full text Add to dashboard Cite

Advanced osteoarthritis (OA) of the ankle is often accompanied by arthritic changes in the subtalar joint, and when arthrodesis is performed for ankle OA, the subtalar joint symptoms remain or even worsen. If the degree of subtalar cartilage degeneration can be quantified, prognosis can be predicted. T1ρ mapping has proven useful for identification of early cartilage degeneration. We hypothesized that T1ρ values of subtalar joint cartilage are higher (i.e., cartilage degeneration is greater) in patients with ankle OA without plain radiographic evidence of subtalar joint space narrowing and osteophytes than in healthy individuals. The T1ρ value of full thickness subtalar joint cartilage was measured on sagittal MR images obtained from 12 patients with ankle OA (3 with Takakura stage 3a disease and 9 with Takakura stage 3b disease) and from 12 healthy individuals. Imaging was performed with a 3.0 T MRI scanner, and PRIDE was used to construct T1ρ maps. A region of interest was set on the water-selective excitation image, which was projected onto the corresponding slice of the T1ρ mapping image to calculate the T1ρ value. The T1ρ value of the subtalar cartilage in patients with ankle OA (41.8 [39.8, 44.4] ms) did not differ significantly from that in healthy individuals (45.0 [37.0, 50.2] ms) (p=0.219 by Mann-Whitney U test). Our findings suggest that the T1ρ value of subtalar articular cartilage in patients with stage 3a or 3b ankle OA for whom conventional imaging reveals no OA changes does not differ significantly from that of healthy individuals.

show abstract

Section: Discussionmentioning

confidence: 99%

T1ρ Mapping of Subtalar Articular Cartilage in Patients with Ankle Osteoarthritis

Maki

Haraguchi

Asano

et al. 2021

J St. Marianna Univ

View full text Add to dashboard Cite

show abstract

“… 32 Significant risk factors at the time of injury for subsequent ankle OA include smoking, high body mass index, and age >30 years. 36 , 47 The normal ankle forms a relatively tight mortise, and even slight widening of the mortise may lead to instability. 23 Similarly more subtle instability, as from posterior malleolar fractures, can lead to rapid ankle failure if left untreated.…”

Section: Epidemiology and Pathophysiology Of Ankle Oamentioning

confidence: 99%

Summary Report of the Arthritis Foundation and the American Orthopaedic Foot & Ankle Society’s Symposium on Targets for Osteoarthritis Research: Part 1: Epidemiology, Pathophysiology, and Current Imaging Approaches

Kim

Amendola

Barg

et al. 2022

Foot & Ankle Orthopaedics

View full text Add to dashboard Cite

This first of a 2-part series of articles recounts the key points presented in a collaborative symposium sponsored jointly by the Arthritis Foundation and the American Orthopaedic Foot & Ankle Society with the intent to survey the state of scientific knowledge related to incidence, diagnosis, pathologic mechanisms, and injection treatment options for osteoarthritis (OA) of the foot and ankle. A meeting was held virtually on December 3, 2021. A group of experts were invited to present brief synopses of the current state of knowledge and research in this area. Part 1 overviews areas of epidemiology and pathophysiology, current approaches in imaging, diagnostic and therapeutic injections, and genetics. Opportunities for future research are discussed. The OA scientific community, including funding agencies, academia, industry, and regulatory agencies, must recognize the needs of patients that suffer from arthritis of foot and ankle. The foot and ankle contain a myriad of interrelated joints and tissues that together provide a critical functionality. When this functionality is compromised by OA, significant disability results, yet the foot and ankle are generally understudied by the research community. Level of Evidence: Level V - Review Article/Expert Opinion.

show abstract

“…3 Most ankle OA is posttraumatic. 3,4 It has been estimated that 56% of people who undergo ankle surgery for ankle OA are in employment. 5 Surgical interventions in the form of arthrodesis and total ankle arthroplasty (TAA) are part of the standard management of patients with endstage ankle OA.…”

Section: Introductionmentioning

confidence: 99%

Outcomes in Ankle Replacement Study (OARS)

Smith,

Dainty,

Loveday

et al. 2023

Bone Joint J

View full text Add to dashboard Cite

AimsThe aim of this study was to capture 12-month outcomes from a representative multicentre cohort of patients undergoing total ankle arthroplasty (TAA), describe the pattern of patient-reported outcome measures (PROMs) at 12 months, and identify predictors of these outcome measures.MethodsPatients listed for a primary TAA at 19 NHS hospitals between February 2016 and October 2017 were eligible. PROMs data were collected preoperatively and at six and 12 months including: Manchester-Oxford Foot and Ankle Questionnaire (MOXFQ (foot and ankle)) and the EuroQol five-dimension five-level questionnaire (EQ-5D-5L). Radiological pre- and postoperative data included Kellgren-Lawrence score and implant position measurement. This was supplemented by data from the National Joint Registry through record linkage to determine: American Society of Anesthesiologists (ASA) grade at index procedure; indication for surgery, index ankle previous fracture; tibial hind foot alignment; additional surgery at the time of TAA; and implant type. Multivariate regression models assessed outcomes, and the relationship between MOXFQ and EQ-5D-5L outcomes, with patient characteristics.ResultsData from 238 patients were analyzed. There were significant improvements in MOXFQ and EQ-5D-5L among people who underwent TAA at six- and 12-month assessments compared with preoperative scores (p < 0.001). Most improvement occurred between preoperative and six months, with little further improvement at 12 months. A greater improvement in MOXFQ outcome postoperatively was associated with older age and more advanced radiological signs of ankle osteoarthritis at baseline.ConclusionTAA significantly benefits patients with end-stage ankle disease. The lack of substantial further overall change between six and 12 months suggests that capturing PROMs at six months is sufficient to assess the success of the procedure. Older patients and those with advanced radiological disease had the greater gains. These outcome predictors can be used to counsel younger patients and those with earlier ankle disease on the expectations of TAA.Cite this article: Bone Joint J 2023;105-B(8):895–904.

show abstract

Incidence and progression of ankle osteoarthritis: The johnston county osteoarthritis project

Cited by 21 publications

References 29 publications

T1ρ Mapping of Subtalar Articular Cartilage in Patients with Ankle Osteoarthritis

T1ρ Mapping of Subtalar Articular Cartilage in Patients with Ankle Osteoarthritis

Summary Report of the Arthritis Foundation and the American Orthopaedic Foot & Ankle Society’s Symposium on Targets for Osteoarthritis Research: Part 1: Epidemiology, Pathophysiology, and Current Imaging Approaches

Outcomes in Ankle Replacement Study (OARS)

Contact Info

Product

Resources

About