Incidence and progression of ankle osteoarthritis: the Johnston county osteoarthritis project

Abstract

significant difference (P<0.05) between the effective rate of the experimental group and that of the control group. All indicators of KOOS were improved, with the significant differences in symptom score, sports score and entertainment ability score, and the life quality reladsvblmadmted to the knee (P < 0.05). The levels of serumIL-1b,TNFa were all decreased in the experimental group, with a significant difference in the degree of IL-1b decrease (P<0.05). Conclusions: Qufengzhitong Capsule is effective in the treatment of chronic knee osteoarthritis and its mechanism may be related to the regulation of the expression of serum IL-1b and TNF-a of patients with chronic knee osteoarthritis.

Prevalence of radiographic ankle osteoarthritis in different subgroups of patients referred for ankle radiography

“…The higher prevalence of radiographic ankle OA in men is consistent with one other study [8], but is contrary to another study that reports more symptomatic ankle OA in women [1]. As the prevalence of ankle and/or foot pain is higher in women, this might explain the contradicting association between sex and symptomatic compared to radiographic ankle OA [25].…”

“…We did not adjust for determinants reported in other studies such as occupation, smoking status, ethnicity, concomitant foot or knee joint OA, knee joint hypermobility and foot structure [1,5,6,8,22,24], as they were not available. Due to the cross-sectional study design, no causal inferences can be drawn from the reported associations.…”

“…In general OA is more common in women, older and obese people [7]. Though, studies on the association between Body Mass Index (BMI), age, sex and ankle OA are inconclusive; some found that ankle OA is more common in overweight and in obese, in women than in men, while others state the opposite or found no associations between ankle OA and age, sex and/or BMI [1,5,[8][9][10].…”