Incidence and Risk Factors for Venous Reflux in the General Population: Edinburgh Vein Study

Abstract

For every year of follow-up, around 1% of this adult population developed venous reflux. In two thirds of cases, the superficial system was affected. Venous reflux increased the risk of developing varicose veins, especially when combined deep and superficial reflux was present.

Progression of varicose veins and chronic venous insufficiency in the general population in the Edinburgh Vein Study

“…In that analysis, the incidence of varicose veins, compared with incidence if there was no reflux, was progressively higher with superficial reflux only and then with combined deep and superficial reflux. 23 Risks related to reflux may begin at an early age; in school children in Bochum, a preclinical refluxing superficial vein led to a 30% risk of trunk varicose veins within 4 years. 24 In contrast to our findings on progression, we found that reflux in the great saphenous vein, at the origin and lower thigh, was particularly important in development of new trunk varices, 23 as also noted in a study comparing reflux in patients with varicose veins and healthy controls.…”

Risk Factors of Saphenous Vein Insufficiency in Female Patients in Riyadh, Saudi Arabia

“…The results vary according to the geographic location and the population being studied [7][8][9]. The Edinburgh Vein Study reported that the prevalence of all categories of varicose veins and CVI increased with age (p < 0.001), while no relation was found with social class [15]. The same study investigated the lifestyle risk factors in another paper.…”

“…Vein Study showed that the prevalence of all categories of varicose veins and CVI increased with age (p< 0.001), while no relation was found with social class [15]. It was also reported that obesity, previous pregnancy, lower use of oral contraceptive pills, mobility at work may be implicated in venous reflux in women [23].…”

“…However, the success of this relatively novel technique is limited by some post-procedure complications like post-procedure pain, phlebitis, and tenderness, for instance [12][13][14]. Yet, data on risk factors of saphenous vein insufficiency is scarce and confusing in medical literature, especially in the gulf area and Arab region [15].…”

Comparative Study of the Original Technology of Micronization of the Purified Flavonoid Fraction of “Detralex®” and the Technology of Micronization of Drugs D and N of the Ukrainian Manufacturers

“…CVI includes varicose veins, post-thrombotic syndrome, primary venous insufficiency, and compression syndromes. This disease characterized by a high prevalence of up to 42% among women and 18% among men [1]. Treatment should be complex and include compression techniques, conservative, and surgical methods.…”