Incidence and Risk Factors of Retinopathy of Prematurity From 2 Neonatal Intensive Care Units in a Hong Kong Chinese Population

Abstract

In VLBW preterm Chinese infants, lower GA, lighter BW, and intraventricular hemorrhage were significant risk factors for ROP, whereas preeclampsia and eclampsia were protective.

Retinopathy of prematurity: applicability and compliance of guidelines in Hong Kong

“…Despite the larger neonatal care units being under the same government umbrella, there is currently no ROP registry among neonatologists and ophthalmologists in the region, which would be helpful for the standardisation of treatment protocols and guidelines for managing preterm infants of ROP. Another local study by Yau et al 25 using the Royal College of Ophthalmologists ROP screening guideline reported an incidence of ROP and type 1 ROP of 18.% and 3.7%, respectively, which is comparable to our study. Within the 7 years of screening in our data, none of the infants who exceeded the UK screening criteria developed ROP, and we believe the yield of detecting treatable ROP in infants beyond the UK screening criteria is low, while taking into consideration cost-effectiveness in our public health system and avoiding unnecessary screening.…”

Retinopathy of Prematurity Among Very Low-Birth-Weight Infants in China: Incidence and Perinatal Risk Factors

“…In our study, the incidence of ROP among VLBW infants with GA < 32 weeks was 30.5%, similar to the incidence reported in Saudi Arabia (37.4%) by Binkhathlan et al 13 The incidence of stage ‡3 ROP in our study was 3.2%, significantly higher in infants delivered at <32 weeks or with BW < 1000 g and consistent with the findings of other Chinese studies. 14,15 Moreover, no infant had stage 4 or stage 5 ROP in our study. With the increased awareness of the risk of blindness caused by ROP, the Chinese Ministry of Health guidelines for the prevention and treatment of ROP were published in 2004.…”

Screening Tool for Early Postnatal Prediction of Retinopathy of Prematurity in Preterm Newborns (STEP-ROP)

“…When a model was created using just GA25 and BW750, statistical measures were optimized with a score cutoff of 2 (SE = Along with low birth weight and gestational age, severity of illness (including RDS, sepsis, patent ductus arteriosus, interventricular hemorrhage, requiring blood transfusions, etc.) is also a contributor to ROP risk [16] . These risk factors are controversial, however, and tend to occur more frequently in the youngest infants.…”