Incidence and risk factors of chronic thromboembolic pulmonary hypertension after acute pulmonary embolism: a systematic review and meta-analysis of cohort studies

Zhang, Meng; Wang, Ning; Zhai, Zhenguo; Zhang, Mingyuan; Zhou, Rongrong; Liu, Yanyan; Yang, Yuanhua

doi:10.21037/jtd.2018.07.106

Cited by 42 publications

(53 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Of those who present with acute pulmonary embolism it is widely reported that approximately 3% (27,28) of these individuals will develop chronic thromboembolic disease (CTED) or chronic thromboembolic pulmonary hypertension (CTEPH). Of these patients a proportion are able to undergo curative surgery-pulmonary endarterectomy (PEA).…”

Section: Non-pharmacological Therapies For Phmentioning

confidence: 99%

Key topics in pulmonary vascular diseases (assembly 13) from the European Respiratory Society 2018 Parisian Congress

2018

View full text Add to dashboard Cite

Section: Non-pharmacological Therapies For Phmentioning

confidence: 99%

Key topics in pulmonary vascular diseases (assembly 13) from the European Respiratory Society 2018 Parisian Congress

2018

View full text Add to dashboard Cite

“…Studies with a score of >5 will be defined as high-quality studies. Studies with a score of ≤5 will be defined as low-quality studies 22…”

Section: Types Of Participantsmentioning

confidence: 99%

Risk factors for predicting progression from normal cognition to mild cognitive impairment: protocol for a systematic review and meta-analysis of cohort studies

Wang

Zhou

et al. 2019

BMJ Open

View full text Add to dashboard Cite

IntroductionMild cognitive impairment (MCI) often represents the earliest stage of Alzheimer’s disease. There has been considerable research investigating specific risk factors regarding the progression from normal cognition to MCI. However, different studies have come to different conclusions on the impact of particular risk factors. Therefore, it is necessary to conduct a meta-analysis of the risk factors that predict cognitive disruption in individuals based on associations with MCI.Methods and analysisWe will search seven electronic databases without time limit, including MEDLINE, EMBASE, The Cochrane Library, Web of Science, China National Knowledge Infrastructure, the Wan Fang Database and China Biology Medicine. Two researchers will independently screen for eligibility and perform data extraction. Data were extracted from cohort studies meeting the inclusive criteria according to the Newcastle Ottawa Scale (NOS) methods. A third member of the research team will be contacted when a consensus cannot be reached. Any disagreement will be settled by consensus. The NOS will be used to assess the quality of the studies. All analyses were performed using Stata V.15.1.Ethics and disseminationWe will report this review in accordance with the Preferred Reporting Items for Systematic Review and Meta-Analysis statement. We will disseminate our findings through a publication in a peer-reviewed journal. This systematic review does not require ethical approval as no primary data are collected.PROSPERO registration numberCRD42018109099.

show abstract

“…M. Zhang и соавт. (2018) в своем систематическом обзоре и метаанализе 15 когортных исследований приходят к выводу: ХТЭЛГ не является редким осложнением острой ТЭЛА, причем авторы отмечают особую важность проведения тщательного выявления и применения комплексного системного подхода в проводимом скрининге, особенно у пациентов группы риска [4].…”

Section: эпидемиологияunclassified

“…Патогенез ЛГ при ХТЭЛГ считается многофакторным, с вовлечением как крупных легочных сосудов, так и микроциркуляторного русла, однако многие его аспекты в настоящее время остаются неизвестными [6]. Анамнестические данные 75% пациентов с ХТЭЛГ указывают на ранее перенесенную острую ТЭЛА, а оставшиеся 25% имеют рецидив ТЭЛА или бессимптомное течение эмболии [4]. Кроме того, только несколько факторов риска, связанных с ТЭЛА, взаимосвязаны с развитием ХТЭЛГ, что указывает на возможные различные патофизиологические механизмы [8].…”

Section: патофизиология и факторы рискаunclassified

“…На сегодняшний день остаются также неясными потенциальные факторы риска ХТЭЛГ среди пациентов, ранее перенесших ТЭЛА. Однако некоторые из них известны: молодой или пожилой возраст, идиопатическая ТЭЛА, ранняя/рецидивирующая ТЭЛА или предшествующая ВТЭ, высокое давление легочной артерии (ЛА) [4]. Факторы риска для ХТЭЛГ и острой ТЭЛА различаются.…”

Section: патофизиология и факторы рискаunclassified

See 1 more Smart Citation

Patient's way from acute pulmonary embolism to chronic thromboembolic pulmonary hypertension: diagnostic and treatment options

Edemskiy

Иванов

Кливер

et al. 2019

Terapevticheskii arkhiv

View full text Add to dashboard Cite

Сhronic thromboembolic pulmonary hypertension (CTEPH) is a serious, under - diagnosed but potentially curable complication of pulmonary embolism (PE) due to medicine advancements. Lack of specific symptoms and signs makes its diagnosis challenging, requiring clinicians to be ready to suspect its presence in patients with dyspnea of unknown origin or persistent symptoms after the pulmonary embolism event. The success of the treatment of this disease depends entirely on early diagnosis. The complexity of the differential diagnosis is due to the problematic aspects including the lack of doctors' awareness of both the pathology itself and the possibilities of its modern treatment. Recently, in our country, the problem of the availability of expert centers with sufficient experience in providing highly specialized medical care to this rather difficult category of patients who need specific therapy has become very actual. The aim of this review is to provide contemporary information about epidemiology, pathophysiology, and clinical features of treating patients with CTEPH, and also, to increase awareness of potential PE→CTEPH transformation. In the article a 4-year - period of experience of the Meshalkin National Medical Research Center on management of CTEPH patients has been presented.

show abstract

Incidence and risk factors of chronic thromboembolic pulmonary hypertension after acute pulmonary embolism: a systematic review and meta-analysis of cohort studies

Abstract: CTEPH is not a rare complication of acute PE. Close follow-up and implementation of a comprehensive screening program are important, especially in patients with independent risk factors.

Cited by 42 publications

References 23 publications

Key topics in pulmonary vascular diseases (assembly 13) from the European Respiratory Society 2018 Parisian Congress

Key topics in pulmonary vascular diseases (assembly 13) from the European Respiratory Society 2018 Parisian Congress

Risk factors for predicting progression from normal cognition to mild cognitive impairment: protocol for a systematic review and meta-analysis of cohort studies

Patient's way from acute pulmonary embolism to chronic thromboembolic pulmonary hypertension: diagnostic and treatment options

Contact Info

Product

Resources

About