Incidence and risk factors of late adverse reactions to low-osmolar contrast media: A prospective observational study of 10,540 exposures

Kang, Dong Yoon; Lee, Suh Young; Ahn, Yoon Hae; Yoon, Soon Ho; Choi, Young Hoon; Lee, Whal; Kang, Hye-Ryun

doi:10.1016/j.ejrad.2021.110101

Cited by 4 publications

(1 citation statement)

References 31 publications

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“…However, most delayed HSRs occur within one week. 41 The incidence of delayed HSR was significantly higher in nonionic dimer contrast media users than in nonionic monomer users. 42 Delayed HSRs were reported to have more frequent cross-reactivity between ICMs than immediate HSRs.…”

Section: Diagnosis and Prevention Of Delayed Hsrs To Icmmentioning

confidence: 88%

Diagnosis and Prevention of Hypersensitivity Reactions to Iodinated Contrast Media

Kang

Jeong

Brockow

2022

Allergy Asthma Immunol Res

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Iodinated contrast media (ICM) have become one of the major causes of drug hypersensitivity reactions (HSRs) related to increasing numbers of ICM-based radiological imaging procedures. Strategies for diagnosing and preventing ICM-induced HSRs have not been uniformly standardized yet. However, advances have been made based on the results of recent research. A previous history of hypersensitivity to ICM is the most significant risk factor for developing HSR by ICM. Avoidance of culprit agents and premedication is the main strategy to prevent recurrences of HSRs in high-risk patients. In addition, we strongly recommend identifying sensitized ICM using skin tests to determine immunoglobulin E-mediated or delayed-type allergy and to guide the choice of an alternative contrast agent. ICM provocation test procedures have been established and are helpful in selected cases. In this paper, we review how to evaluate patients who have experienced immediate or delayed HSRs caused by ICM to minimize the risk of recurrence and discuss unmet needs that require further research.

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Section: Diagnosis and Prevention Of Delayed Hsrs To Icmmentioning

confidence: 88%