Incidence, Causes and Mechanism of Hypercalcaemia in a Hospital Population in Hong Kong

Shek, Chi Chung; Natkunam, A.; Tsang, Victor; Cockram, Clive S.; Swaminathan, R.

doi:10.1093/qjmed/77.3.1277

Cited by 39 publications

(32 citation statements)

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“…The reason may be that our site, located in southern part of Japan, has a low prevalence of sarcoidosis in general. Tuberculosis was shown to be an important cause of hypercalcemia in two Hong Kong studies (9,32), although the present study found no case of tuberculosis. Another reason for these variations may be the time of data collection, since the incidence of granulomatous diseases may fluctuate over time (33).…”

Section: The Major Causes Of Hypercalcemia Were Found To Be Malignanccontrasting

confidence: 83%

“…On the other hand, breast carcinoma was relatively uncommon in our series as well as in other Asian studies (9,10), in contrast to Western series with this carcinoma typically accounting for more than 20% (3,6,(17)(18)(19). The low prevalence of hypercalcemia due to breast carcinoma may reflect the low incidence of this tumor in Asia (9), while the high prevalence of hypercalcemia due to ATL may be due to the high incidence of this hematologic malignancy in Okinawa and southern areas of Japan (20)(21)(22)(23). Furthermore, ATL is more prevalent in the southern area of Japan than in northern areas (24).…”

Section: The Major Causes Of Hypercalcemia Were Found To Be Malignancsupporting

confidence: 66%

“…On the other hand, one study, reported from a hospitalized population in Hong Kong, showed that PHP was relatively uncommon (5.5%) (9). Two reports from Taiwan also noted this point (10,30 We detected no cases of granulomatous diseases.…”

Section: The Major Causes Of Hypercalcemia Were Found To Be Malignancsupporting

confidence: 44%

See 2 more Smart Citations

The Causes of Hypercalcemia in Okinawan Patients: AnInternational Comparison

2007

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Section: The Major Causes Of Hypercalcemia Were Found To Be Malignanccontrasting

confidence: 83%

Section: The Major Causes Of Hypercalcemia Were Found To Be Malignancsupporting

confidence: 66%

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The Causes of Hypercalcemia in Okinawan Patients: AnInternational Comparison

2007

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“…Patients with hypercalcemia often demonstrate more extensive pulmonary involvement, but the association with disease severity is inconsistent (103,104,111). Hypercalcemia has been less frequently noted in conjunction with extrapulmonary disease, including miliary infection, peritonitis, and osteomyelitis (111)(112)(113)(114).…”

Section: Hypercalcemiamentioning

confidence: 99%

“…Hypercalcemia has been less frequently noted in conjunction with extrapulmonary disease, including miliary infection, peritonitis, and osteomyelitis (111)(112)(113)(114). Frequently, hypercalcemia is not noted at the time of diagnosis but occurs early in the course of treatment (103,111). Initial assessments may not account for disease-related hypoalbuminemia, and hypercalcemia may appear only as the serum albumin increases during treatment, reflecting an improvement in nutritional status (115).…”

Section: Hypercalcemiamentioning

confidence: 99%

Endocrine and Metabolic Aspects of Tuberculosis

Vinnard

Blumberg

2021

Tuberculosis and Nontuberculous Mycobacterial Infections

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Endocrine and metabolic derangements are infrequent in patients with tuberculosis, but they are important when they occur. The basis for these abnormalities is complex. While Mycobacterium tuberculosis has been described to infect virtually every endocrine gland, the incidence of gland involvement is low, especially in the era of effective antituberculosis therapy. Furthermore, endocrine and metabolic abnormalities do not always reflect direct infection of the gland but may result from physiological response or as a consequence of therapy. Metabolic disease may also predispose patients to the development of active tuberculosis, particularly in the case of diabetes mellitus. While hormonal therapy may be necessary in some instances, frequently these endocrine complications do not require specific interventions other than antituberculous therapy itself. With the exception of diabetes mellitus, which will be covered elsewhere, this chapter reviews the endocrinologic and metabolic issues related to tuberculosis.

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Surgical Treatment for Primary Hyperparathyroidism in Hong Kong

Chan²,

Kung³

et al. 2004

Arch Surg

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Hypothesis: With the introduction of the blood chemistry multichannel autoanalyzer, primary hyperparathyroidism (HPT) is increasingly diagnosed. The clinical pattern of primary HPT has undergone a significant evolution in Western countries. A similar change can be documented in a geographic region where this condition is considered to be relatively uncommon. Design: Unselected case series. Setting: A tertiary referral endocrine surgical unit. Patients: All patients with primary HPT surgically treated over the past 30 years. Main Outcome Measures: The prevalence of patients per 100000 hospital admissions, clinical presentation, biochemistry study results, pathologic status, and main outcome were compared over three 10-year spans according to the introduction of the multichannel au

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Incidence, Causes and Mechanism of Hypercalcaemia in a Hospital Population in Hong Kong

Cited by 39 publications

References 0 publications

The Causes of Hypercalcemia in Okinawan Patients: AnInternational Comparison

The Causes of Hypercalcemia in Okinawan Patients: AnInternational Comparison

Endocrine and Metabolic Aspects of Tuberculosis

Surgical Treatment for Primary Hyperparathyroidism in Hong Kong

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