Introduction:The hand represents the tool of tools. She is interested in various traumatic but also nontraumatic pathologies. Purpose: To study the epidemiological aspects of non-traumatic pathplogies of the hand and wrist. Patients and Methods: This was a continuous, descriptive and analytical retrospective study over a period of 5 years from january2017 to December 2021. Results: There were 307 patients, 171 women and 136 men with an average age of 39,54 years (Range 03 months and 82 years). Manuel workers and housewives were the most representative with 30,5% and 24% respectively. The right side was affected in 66,3% of cases. The preferred location was the wrist in 47,9% of cases. Degenerative and/or inflammatory pathologies were the most common in 32,9% of cases. Women presented a degerarative and/or inflammatory pathology in 65,3% of cases and men, an infectious pathology in 58,1% of cases. Conclusion: Non-traumatic pathologies of the hand and wrist are diverse and varied. Their treatment should not be delayed for a favorable outcome.