Incidence of Acute Diarrhea-Associated Death among Children < 5 Years of Age in Bangladesh, 2010–12

Abstract

Although acute diarrheal deaths have declined globally among children < 5 years, it may still contribute to childhood mortality as an underlying or contributing cause. The aim of this project was to estimate the incidence of acute diarrhea-associated deaths, regardless of primary cause, among children < 5 years in Bangladesh during 2010-12. We conducted a survey in 20 unions (administrative units) within the catchment areas of 10 tertiary hospitals in Bangladesh. Through social networks, our field team identified households where children < 5 years were reported to have died during 2010-12. Trained data collectors interviewed caregivers of the deceased children and recorded illness symptoms, health care seeking, and other information using an abbreviated international verbal autopsy questionnaire. We classified the deceased based upon the presence of diarrhea before death. We identified 880 deaths, of which 36 (4%) died after the development of acute diarrhea, 17 (2%) had diarrhea-only in the illness preceding death, and 19 (53%) had cough or difficulty breathing in addition to diarrhea. The estimated annual incidence of all-cause mortality in the unions < 13.6 km of the tertiary hospitals was 26 (95% confidence interval [CI] 16-37) per 1,000 live births compared with the mortality rate of 37 (95% CI 26-49) per 1,000 live births in the unions located ≥ 13.6 km. Diarrhea contributes to childhood death at a higher proportion than when considering it only as the sole underlying cause of death. These data support the use of interventions aimed at preventing acute diarrhea, especially available vaccinations for common etiologies, such as rotavirus.

Short-Term Effects of Climate Variability on Childhood Diarrhoea in Bangladesh: Multi-Site Time-Series Regression Analysis

“…Another reason could be that under-five-year-old males are more commonly affected by diarrhoea than females [ 24 ], or possibly because males are genetically more susceptible to infectious diseases, including diarrhoea [ 24 , 25 ]. The median age in our study was slightly higher (12 months vs. 9.5) than in other studies on childhood diarrhoea mortality, with a narrower interquartile range (8–18 months vs. 6–24) [ 26 ].…”

Molecular detection of Vibrio cholerae from human stool collected from SK Hospital, Mymensingh, and their antibiogram

“…Cholera is a disease mostly associated with poor sanitation. Diarrheal disease is known to be a major cause of child mortality in Bangladesh [29]. Vibrio cholerae is a major etiology of diarrhea leading to death.…”

Risk Factors of Childhood Diarrhoeal Diseases in Bangladesh: Evidence from a Nationwide Cross-sectional Survey

“…Diarrhoea is the condition showing the frequent and excessive discharge of or loose stools from the bowel. Although deaths due to diarrhoea has been declined globally (Ahmed et al, 2018), it still remains the second major causes of deaths among under-five children (Workie et al, 2018), and according to the World Health Organization, there are nearly 1.7 billion cases of diarrhoea occurred every year worldwide among children under five (Sarker, 2016;Peter and Umar, 2018;WHO, 2017). A recent report by the International Vaccine Access Center (IVAC), Johns Hopkins Bloomberg School of Public Health reveals that about 1200 young children die due to diarrhoea every day which means that it claimed the lives of Research Article Submission Date: March, 25 2021 Acceptance Date: April, 9 2021 99 approximately 4,37,000 children per year (Pneumonia and Diarrhea Progress Report 2020).…”