Incidence of Acute Otitis Media

Pukander, J.; Luotonen, Jukka; Sipilä, Markku; Timonen, M.; Karma, Pekka

doi:10.3109/00016488209130903

Cited by 78 publications

(31 citation statements)

References 15 publications

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“…In our series, AOM was found more frequently in boys than in girls. This is the case in most studies [11]. According to Teele et al [2], logistic regression shows that males are more at risk of AOM than females, in each of the age groups studied bY those authors.…”

Section: Discussionmentioning

confidence: 90%

Acute otitis media in childhood: A study of 20,532 cases

et al. 1995

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We present a study of acute otitis media among 20,532 Spanish children during a 6-month period from January through June 1991. The study was done by distributing a questionnaire to all Spanish pediatricians. Of the patients 51.7% were girls and 48.3% boys; 68.7% of all children were younger than 5 years. The most frequent symptoms were otalgia or irritability, 92.7%; fever, 63.5%; otorrhea, 24.9%; vomiting, 21.4%; and another concomitant upper respiratory tract infection, 65.5%. Otitis was bilateral in 45.6% of the cases. The most frequently used antibiotic was cefixime (38%), followed by amoxicillin-clavulanate (22.2%), amoxicillin (15.3%), 2nd-generation cephalosporins (13.5%) and macrolides (8.8%). In 11.8% of the patients, a change in the initial antibiotic therapy was required due to adverse effects. Resolution of symptoms occurred in 77.8% of the patients.

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Section: Discussionmentioning

confidence: 90%

Acute otitis media in childhood: A study of 20,532 cases

et al. 1995

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“…Among children in Finland, the annual incidence of otitis media was 38 and 28% for boys and girls, respectively (33), and in one American study conducted in Boston, it was 62% for boys and girls combined (34).…”

Section: Discussionmentioning

confidence: 99%

Susceptibility to infections and immune status in Inuit infants exposed to organochlorines.

Dewailly

Ayotte

Bruneau

et al. 2000

Environ Health Perspect

229

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We investigated whether organochlorine exposure is associated with the incidence of infectious diseases in Inuit infants from Nunavik (Arctic Quebec, Canada). We compiled the number of infectious disease episodes during the first year of life for 98 breast-fed and 73 bottle-fed infants. Concentrations of organochlorines were measured in early breast milk samples and used as surrogates to prenatal exposure levels. Immune system parameters were determined in venous blood samples collected from infants at 3, 7, and 12 months of age. Otitis media was the most frequent disease, with 80. 0% of breast-fed and 81.3% of bottle-fed infants experiencing at least one episode during the first year of life. During the second follow-up period, the risk of otitis media increased with prenatal exposure to p,p'-DDE, hexachlorobenzene, and dieldrin. The relative risk (RR) for 4- to 7-month-old infants in the highest tertile of p, p'-DDE exposure as compared to infants in the lowest tertile was 1. 87 [95% confidence interval (CI), 1.07-3.26]. The RR of otitis media over the entire first year of life also increased with prenatal exposure to p,p'-DDE (RR, 1.52; CI, 1.05-2.22) and hexachlorobenzene (RR, 1.49; CI, 1.10-2.03). Furthermore, the RR of recurrent otitis media ( [Greater/equal to] 3 episodes) increased with prenatal exposure to these compounds. No clinically relevant differences were noted between breast-fed and bottle-fed infants with regard to immunologic parameters, and prenatal organochlorine exposure was not associated with immunologic parameters. We conclude that prenatal organochlorine exposure could be a risk factor for acute otitis media in Inuit infants. Images Figure 1

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“…However, because some of the signs/symptoms diagnostic for AOM overlap those for a cold-like illness (CLI) which is most often the appreciable expression of a viral upper respiratory tract infection (vURI) and a known precipitant of OM 10-13 , clinical certainty with respect to assignment to this subcategory is undermined. Also, many studies of AOM incidence abstracted the reported presentations from large data bases representing multiple health care providers [14][15][16][17] , and given the variable the skills of the contributing physicians 18 , the quality of those data is uncertain.…”

Section: Introductionmentioning

confidence: 99%