Incidence of Acute Pancreatitis in Albanian Population

Abstract

Background:Acute Pancreatitis (AP) is an inflammatory pathology with large regional variations in incidence and etiologyAim:The aim of the study was to provide a description of the epidemiologic situation of AP in Albanian population, regarding incidence, etiology and severity of the diseaseMethods:We have studied all the files of all patients with acute pancreatitis admitted at the UHC ‘Mother Theresa” during an eight year period (2005-2012).The results:We had 964 admissions with the diagnosis acute pancreatitis, making an incidence of 5.64 per 100 000 inhabitants per year. Mean age of patients was 54.5 ± 16.93 years old. Among risk factors, alcohol consumption was found in 382 patients (39.6%), gallstone in 362 patients (37.6%), and others in 220 patients (22.8%).Conclusion:The incidence of acute pancreatitis in Albania ranges from 3.6 – 5.64 new cases per 100 000 inhabitants per year, with an increasing trend during the last years. The incidence of AP among females almost doubles during 2005-2012. Alcohol consumption is the predominating etiologic factor among young males.

The incidence and aetiology of acute pancreatitis across Europe

“…Table 2 shows population-based incidence rates for acute pancreatitis reported across Europe from 1989 to 2015. Incidence ranged from 4.6 per 100 000 in Tirana, Albania (from 2005 to 2012) [8], to 100 per 100 000 in the Świętokrzyskie Voivodeship province of Poland in 2011 [9].…”

“…Table 3 shows the three main aetiologies of acute pancreatitis (alcohol, gallstone and other or idiopathic aetiology) reported from studies across Europe. Of 11 studies from eastern Europe, seven (64%) had a higher ratio of alcohol to gallstone aetiologies [10,[24][25][26][27][28]77], which is significantly higher than for two of 16 studies from southern Europe (13%; p=0.012) [8,30], and for three of 21 studies from northern Europe (14%; p=0.013) [29,31], although not significantly different to three of nine studies from western Europe (33%; p=0.37) [28,32].…”

A systematic review and meta-analysis of the aetiology of acute pancreatitis

“…One international study 8 presented data from the US, Mexico, South America, Europe and Asia that were analysed separately in subgroup analyses by geographic region. The subgroup analysis with studies that used population coded diagnoses 7,10,14,17,25,27,34,35,46,47 and studies that diagnosed the aetiology of AP based on chart reviews for all study patients 8,9,[11][12][13]15,16,[18][19][20][21][22][23][24]26,[28][29][30][31][32][33][36][37][38][39][40][41][42][43][44][45]48 are summarized in Fig. 2a-c.…”

Pancreatogenic Diabetes: Triggering Effects of Alcohol and HIV

“…While the aforementioned rates reflect the combined incidence of pancreatitis, varying rates have been reported in different settings. For example, Albania (5.6/100,000) [ 55 ], Czech Republic (17/100000) [ 56 ], Germany (13/100000) [ 57 ] and the Netherlands (19.2/100,000) [ 58 ] reported lower incidences of acute pancreatitis, while Croatia (30.2/100,000) [ 59 ], Denmark (35/100,000) [ 60 ], Scotland (41.9/100,000) [ 61 ], Spain (67/100,000) [ 62 ], Finland (73.4/100,000) [ 63 ] and Poland (100/10,000) [ 64 ] have reported higher rates. Meanwhile, the global prevalence of pancreatitis has continued to increase.…”