2020
DOI: 10.4103/iju.iju_261_20
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Incidence of adenocarcinoma bladder in patients with cystitis cystica et glandularis: A retrospective study

Abstract: Introduction: Cystitis cystica et glandularis (CCG) is a hyper proliferative condition, likely representing a local immune response to chronic inflammatory stimulus. It has been hypothesized as a potential precursor of adenocarcinoma; however, a definite association has not been demonstrated. We aimed to determine whether CCG is a precursor to malignancy and to study the correlation of its two histological variants: the typical and the intestinal metaplasia (IM) type CCG. Materials … Show more

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Cited by 13 publications
(12 citation statements)
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“…The reason for the high incidence of proliferative cystitis in PL remained unclear, UTI and lymphatic and venous stasis had been implicated with controversy 1,7,8 . It has been postulated that proliferative cystitis, especially cystitis glandularis may be a premalignant lesion of bladder adenocarcinoma, 9 but such an association has been refuted more recently 10,11 …”
Section: Discussionmentioning
confidence: 99%
“…The reason for the high incidence of proliferative cystitis in PL remained unclear, UTI and lymphatic and venous stasis had been implicated with controversy 1,7,8 . It has been postulated that proliferative cystitis, especially cystitis glandularis may be a premalignant lesion of bladder adenocarcinoma, 9 but such an association has been refuted more recently 10,11 …”
Section: Discussionmentioning
confidence: 99%
“…The finding of hydronephrosis in this patient is in accordance with the another report which has proven that CG may cause urinary obstruction and even leading to acute renal failure [13] , [14] . Cystitis glandularis usually presented as microscopic finding and urinary bladder mass is extremely rare in the literature [1] , [15] . Therefore, the finding of bladder mass mimicking the characteristic of bladder tumor was a feature which makes this case rare and interesting.…”
Section: Discussionmentioning
confidence: 99%
“…In a recent retrospective analysis of 64 patients with 52 typical and 12 intestinal type CCEG, no difference in the development of malignancy was reported over a median follow-up of 5 years and 5 months. 23 In our study, we evaluated only patients with CCEG without any evidence of malignancy and followed them with a mean follow-up of 32.8 months and did not find any evidence of the development of malignancy.…”
Section: Discussionmentioning
confidence: 99%