Incidence of Adenoviral Conjunctivitis in Patients Referred to the Iran University Affiliated Hospital

Abstract

Background and Aims: Adenovirus is one of the causative agents of viral conjunctivitis. Approximately an average of 40% of viral conjunctivitis is due to adenovirus infection. The rate of infection is usually the highest during the spring and summer months. In this study attempt was made to evaluate the incidence of conjunctivitis due to adenovirus infection in patients referred to one of the affiliated university hospital using the congenital virological methods. Materials and Methods: Samples were taken by a swab from patients with clinical conjunctivitis. Samples were processed and tested using the techniques of cell culture inoculation and polymerase chain reaction. Results: From the 100 samples taken 16% of then were positive by PCR Method. From these only 8% showed viral growth on cell culture. There was no difference of infection between the sex groups but most cases accrued in patients aged 17-27 years during the months of March to May. Conclusion: From the results of this study if was concluded that adenovirus plays a major role as a causative agent of conjunctivitis.

Frequency of adenovirus serotype 8 in patients with Keratoconjunctivitis, in Ahvaz, Iran

“…EKC and pharyngoconjunctival fever are the most common adenoviral ocular diseases (4, 8). Adenoviral keratoconjunctivitis is frequent ophthalmological disease and account for 15% to 70% of all conjunctivitis cases worldwide (3, 9).…”

“…Diagnosis is clinically based on clinical features, and history symptoms. However, other causes of conjunctivitis such as chlamydial infection and herpes simplex virus or varicella zoster virus need to be excluded (9).…”

“…Identification of the adenovirus serotype involved in EKC is required to understand the geographical distribution of the adenovirus and to perfect the knowledge on the relation between a specific genotype and clinical features (4, 13). There is limited data regarding adenoviral kerato-conjunctivitis in Iran (9). The prevalence of EKC have been reported in different regions of the world (4, 13).…”

<p>Epidemiology and molecular diagnosis of acute conjunctivitis in patients attending Hamadan, west Iran ophthalmology clinics 2016–2017</p>

“…Two studies had already been conducted in central Iran. One of these was conducted on 100 patients with eye redness and conjunctivitis symptoms attending a university-affiliated hospital in Tehran, 16 of whom were positive for adenovirus on PCR 16. The other study investigated the prevalence rate of viral causes among patients attending hospitals across Tehran.…”

Molecular epidemiology of human Adenovirus among patients with Keratoconjunctivitis

“…Of all conjunctivitis cases, the global prevalence of adenoviral conjunctivitis has been reported to be between 15 and 70% in both sporadic and epidemic forms. Moreover, epidemic keratoconjunctivitis may break out in large scales in schools, hospitals, and military establishments (Weiss et al, 1993;Shamsi-Shahrabadi et al, 2009). Adenoviruses have been typed differently in various parts of the world.…”