Incidence of and risk factors for postoperative nausea and vomiting at a Japanese Cancer Center: first large-scale study in Japan

Morino, Ryozo; Ozaki, Makoto; Nagata, Osamu; Yokota, Miyuki

doi:10.1007/s00540-012-1468-5

Cited by 47 publications

(43 citation statements)

References 32 publications

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“…In our study use of inhalational anesthetic agents halothane and iso urane were signi cant (p = 0.469) and associated with PONV. This nding is in contrast to the study done in Japan and Nigeria [10,16]. The reason for this could be usage of inhalational anesthetic agents for majority of patients which operated under general anesthesia in the study population (60.1%).…”

Section: Discussioncontrasting

confidence: 68%

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Incidence and Risk Factors associated with Post-operative Nausea and Vomiting in Elective Adult Surgical Patients at Wolaita Sodo Teaching Referral Hospital: An Institutional Based Cross-sectional Study

Temesgen

Wolde

2020

Preprint

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Background Postoperative nausea and vomiting is among the most common postoperative complications, despite modern anesthetics and surgical techniques. It can occur during the operation and persisting in the postoperative period cause reduces patient comfort, delayed discharge from the hospital and an increase in costs. The risk factors that affect the incidence of post-operative nausea and vomiting are multifactorial in origin and occur in 20 to 30% of all patients and can extend up to 60–70% in high-risk patients. The objective of this study was to determine the incidence and associated risk factors of postoperative nausea and vomiting. Methods An institution-based, cross-sectional study was conducted from March to August 2019 in Wolaita Sodo University teaching referral hospital (WSUTRH). A total of 371 adult elective patients who operated during this period were included in the study. Data were collected by interviewing patients and reviewing their cards then entered and analyzed using SPSS version 25. Variables with P value less than < 0.2 in the bivariate analysis were fitted into the multivariable logistic regression analysis to identify factors associated with postoperative nausea and vomiting and a P value of < 0.05 was considered statistically significant. Results The incidence of postoperative nausea and vomiting 24hour after surgery was 29.1%. In multivariable analysis, previous history of PONV (AOR = 5.1, 95%CI = 4.00-6.58), use of opioids (AOR = 4.91, 95%CI = 3.08–10.37), use of inhalational anesthetic agent (AOR = 2.38, 95%CI = 1.45–5.30), and long duration of surgery AOR = 6.65, 95%CI = 5.52–8.30) were significantly associated with the incidence of postoperative nausea and vomiting. Conclusions The incidence of postoperative nausea and vomiting was high compared to other studies done in different settings. Previous history of PONV, use of opioids, use of inhalational anesthetic agents and long duration of surgery are predictors of postoperative nausea and vomiting. We recommend routine preoperative PONV risk evaluation and give antiemetic premedication for those high-risk patients.

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Section: Discussioncontrasting

confidence: 68%

“…A study done at a Japanese cancer center shows the incidence of PONV was 42.6% within the rst 48hrs after operation. Female sex, previous history of PONV, prolonged anesthesia and remifentanil use during surgery were identi ed as risk factors for both nausea and vomiting [10].…”

mentioning

confidence: 99%

Incidence and Risk Factors associated with Post-operative Nausea and Vomiting in Elective Adult Surgical Patients at Wolaita Sodo Teaching Referral Hospital: An Institutional Based Cross-sectional Study

Temesgen

Wolde

2020

Preprint

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“…Despite the introduction of new anaesthetic agents and anaesthesia techniques, the overall incidence of postoperative nausea and vomiting (PONV), which is defined as any nausea, retching and vomiting during the first 24–48 h after surgery, remains 20–40% …”

mentioning

confidence: 99%

Does previous chemotherapy‐induced nausea and vomiting predict postoperative nausea and vomiting?

Silva

Sousa

Guimarães

et al. 2015

Acta Anaesthesiol Scand

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“…While smoking is reported to reduce risk of PONV [13,18,19], there have also been some contradictory reports by Toner et al [10] and Pierre et al [20]. In Singapore, smoking status did not seem to make a significant difference in the risk of PONV.…”

Section: Discussionmentioning

confidence: 78%

Singapore General Hospital Experience on Ethnicity and the Incidence of Postoperative Nausea and Vomiting after Elective Orthopaedic Surgeries

Leong

Kwa

et al. 2015

Journal of Anesthesiology

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Introduction. We explored how ethnicity affects the risk of postoperative nausea and vomiting (PONV) and established the correlation of suggested risk factors of PONV in the multiethnic population of Singapore. Methods. 785 patients who underwent orthopaedic surgery were recruited. These comprised 619 Chinese (78.9%), 76 Malay (9.7%), 68 Indian (8.7%), and 22 other (2.8%) cases. The presence of possible risk factors of PONV and nausea and/or vomiting within 24 h after surgery was studied. Univariate and multivariate logistic regression analyses were performed. Results. The incidence of PONV was 33.2% (261 patients). There was no statistically significant difference of PONV incidence between Chinese, Malay, and Indian cases (34.6% versus 34.2% versus 29.4%, = 0.695). Indian females younger than 50 years were found to have a higher incidence of vomiting ( = 0.02). The significant risk factors for this population include females, use of nitrous oxide, and a history of PONV. Conclusion. In the groups studied, ethnicity is not a significant risk factor for PONV except for young Indian females who have a higher risk of postoperative vomiting. We suggest the selective usage of antiemetic for young Indian females as prophylaxis and avoiding nitrous oxide use in high-risk patients.

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Incidence of and risk factors for postoperative nausea and vomiting at a Japanese Cancer Center: first large-scale study in Japan

Cited by 47 publications

References 32 publications

Incidence and Risk Factors associated with Post-operative Nausea and Vomiting in Elective Adult Surgical Patients at Wolaita Sodo Teaching Referral Hospital: An Institutional Based Cross-sectional Study

Incidence and Risk Factors associated with Post-operative Nausea and Vomiting in Elective Adult Surgical Patients at Wolaita Sodo Teaching Referral Hospital: An Institutional Based Cross-sectional Study

Does previous chemotherapy‐induced nausea and vomiting predict postoperative nausea and vomiting?

Singapore General Hospital Experience on Ethnicity and the Incidence of Postoperative Nausea and Vomiting after Elective Orthopaedic Surgeries

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